Home Cart Sign in  
Chemical Structure| 955978-88-8 Chemical Structure| 955978-88-8

Structure of 955978-88-8

Chemical Structure| 955978-88-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 955978-88-8 ]

CAS No. :955978-88-8
Formula : C8H5FIN
M.W : 261.03
SMILES Code : IC1=C(F)C=CC2=C1C=CN2

Safety of [ 955978-88-8 ]

Application In Synthesis of [ 955978-88-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 955978-88-8 ]

[ 955978-88-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 169674-02-6 ]
  • [ 955978-88-8 ]
YieldReaction ConditionsOperation in experiment
4-chloro-5-fluoro-1 H-pyrrolo[2,3-b]pyridine (500 mg, 2.931 mmol) in dioxane (12 ml.) was warmed to 40 C until a solution resulted. 4M HCI in dioxane solution (800 muIota_, 3.224 mmol) was added dropwise. The reaction mixture was cooled to room temperature and filtered. The solid was washed with diethyl ether and dried. It was then suspended in acetonitrile (10 ml.) and treated with sodium iodide (2.63 g, 17.55 mmol). The reaction mixture was heated at 80 C overnight. After cooling to room temperature, reaction mixture was treated with 1 N sodium hydroxide solution until it was basic. It was then extracted with ethyl acetate and washed with water. The combined organic layers were washed with saturated aqueous sodium chloride solution, dried, filtered and concentrated under reduced pressure to afford 5-fluoro-4-iodo-1 H-indole.
  • 2
  • [ 23077-43-2 ]
  • [ 955978-88-8 ]
 

Historical Records

Technical Information

Categories