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Chemical Structure| 952434-89-8 Chemical Structure| 952434-89-8

Structure of 952434-89-8

Chemical Structure| 952434-89-8

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Product Details of [ 952434-89-8 ]

CAS No. :952434-89-8
Formula : C10H9ClN2O2
M.W : 224.64
SMILES Code : COC1=CC2=C(OC)N=C(Cl)N=C2C=C1

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Application In Synthesis of [ 952434-89-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 952434-89-8 ]

[ 952434-89-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 67-56-1 ]
  • [ 105763-77-7 ]
  • [ 124-41-4 ]
  • [ 952434-89-8 ]
YieldReaction ConditionsOperation in experiment
at 20℃; for 6h; Reference Example 7: Synthesis of 2-chloro-4,6-dimethoxyquinazoline A solution of <strong>[105763-77-7]2,4-dichloro-6-methoxyquinazoline</strong> (0.33 g) in methanol (5 mL) was added sodium methoxide (0.086 g), and the mixture was stirred at room temperature for 6 h. Water was added to the reaction mixture, and the aqueous layer was extracted with chloroform. The organic layer was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (silica gel, chloroform/methanol = 50:1) to obtain 2-chloro-4,6-dimethoxyquinazoline (0.20 g). LC/MS: ESI+ (m/z) 225 (M++1)
 

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