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Chemical Structure| 946428-00-8 Chemical Structure| 946428-00-8

Structure of 946428-00-8

Chemical Structure| 946428-00-8

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Product Details of [ 946428-00-8 ]

CAS No. :946428-00-8
Formula : C10H7BrO2S
M.W : 271.13
SMILES Code : O=C(C1=CSC2=CC(Br)=CC=C21)OC
MDL No. :MFCD27934315

Safety of [ 946428-00-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 946428-00-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 946428-00-8 ]

[ 946428-00-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 67-56-1 ]
  • [ 19075-58-2 ]
  • [ 19075-61-7 ]
  • [ 360576-01-8 ]
  • [ 946428-00-8 ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid; at 65℃; Preparation 18; 6-Bromobenzothiophene-3-carboxylic acid methyl ester and 6-Bromobenzothiophene-2- carboxylic acid methyl ester; A solution of the mixture of 6-Bromobenzothiophene-3-carboxylic acid and 6- Bromobenzothiophene-2-carboxylic acid (6.5 g, 25.28 mmol) and sulfuric acid (4.65 g, <n="28"/>47.43 mmol) in MeOH (100 niL) is heated to 65 C overnight. A light brown solid is visualized. The solution is cooled to room temperature and the solid formed is filtered off and washed with MeOH to give 5.6 g (83%) of the mixture of: 6-Bromobenzothiophene- 3-carboxylic acid methyl ester and 6-Bromobenzothiophene-2-carboxylic acid methyl ester in a ratio 7:3. ES/MS m/e 272 (M+2).
 

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