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Chemical Structure| 940879-48-1 Chemical Structure| 940879-48-1

Structure of 940879-48-1

Chemical Structure| 940879-48-1

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Product Details of [ 940879-48-1 ]

CAS No. :940879-48-1
Formula : C7H11NO2
M.W : 141.17
SMILES Code : CC(C1N=C(C)OC=1C)O
MDL No. :N/A

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Application In Synthesis of [ 940879-48-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 940879-48-1 ]

[ 940879-48-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 75-16-1 ]
  • [ 92901-88-7 ]
  • [ 940879-48-1 ]
YieldReaction ConditionsOperation in experiment
In diethyl ether; at 20℃; for 1h; Preparation 49 l-(2,5-dimethyloxazol-4-yl)ethanol To a solution of <strong>[92901-88-7]2,5-dimethyloxazole-4-carbaldehyde</strong> (1 g, 7.99 mmol) in ether (26.6 ml) at rt was added methylmagnesium bromide (7.99 ml, 1 1.19 mmol) dropwise, and the reaction mixture was stirred at rt for 1 h. Hydrochloric acid ( 11.19 ml, 1 1.19 mmol) was added, and the aqueous layer was extracted with EtOAc (x3). The combined organic layers were washed with brine, dried over anhydrous sodium sulfate, and filtered, and the filtrate was evaporated in vacuo to give the crude product (1.2 g, 100%). This crude product was used without purification. XH NMR (500MHz, CHLOROFORM-d) δ 4.79 (quin, J=6.4 Hz, 1H), 2.41 (s, 3H), 2.30 (s, 3H), 1.53 (d, J=6.6 Hz, 3H).
 

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