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Chemical Structure| 936482-02-9 Chemical Structure| 936482-02-9

Structure of 936482-02-9

Chemical Structure| 936482-02-9

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Product Details of [ 936482-02-9 ]

CAS No. :936482-02-9
Formula : C8H14N2O2S
M.W : 202.27
SMILES Code : N#CC1CCN(S(=O)(CC)=O)CC1
MDL No. :MFCD11099947

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Application In Synthesis of [ 936482-02-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 936482-02-9 ]

[ 936482-02-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 240401-22-3 ]
  • [ 594-44-5 ]
  • [ 936482-02-9 ]
YieldReaction ConditionsOperation in experiment
In a dry round bottom flask was placed <strong>[240401-22-3]4-cyanopiperidinium chloride</strong> (13, 5g, 45.4 mmol) dichloromethane (150ml) and triethylamine (18.98ml, 136 mmol). To the reaction was added dropwise ethanesulfonyl chloride (4.56 ml, 45.4 mmol) and the solution stirred 1 hour and quenched with water (100 ml). The mixture was extracted with dichloromethane (3x 50 ml) and the combined organic <n="55"/>fractions dried (MgSO4), filtered, and the solvent evaporated under reduced pressure. The residue was purified by column chromatography on silica gel, eluting with EtOAc/Hexanes to give 1- (ethylsulfonyl)pirhoeridine-4-carbonitrile (14) as a white solid. MS 203 (M+l)
 

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