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Chemical Structure| 928196-54-7 Chemical Structure| 928196-54-7

Structure of 928196-54-7

Chemical Structure| 928196-54-7

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Product Details of [ 928196-54-7 ]

CAS No. :928196-54-7
Formula : C6H4ClNO5S
M.W : 237.62
SMILES Code : O=S(C1=CC=CC([N+]([O-])=O)=C1O)(Cl)=O

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Application In Synthesis of [ 928196-54-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 928196-54-7 ]

[ 928196-54-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 603-87-2 ]
  • [ 928196-54-7 ]
YieldReaction ConditionsOperation in experiment
Bl 2-Hydroxy-3-nitro-benzenesulfonyl chloride; 2.30 g (14.9 mMol) of <strong>[603-87-2]2-amino-6-nitro-phenol</strong> [PCT Int. Appl. WO 9611917 Al] was suspended in 7.8 rnL aq. HCl (37%) and 3.2 rnL of acetic acid and the mixture was cooled down to - 5 0C; then, a solution of 1.13 g (1.1 eq.) of sodium nitrite in 1.8 mL water was added drop by drop. After stirring at 0 0C for 45 min, this reaction mixture was dropped into a saturated solution of sulfur dioxide in acetic acid at 0 0C, which contained 0.46 g (0.3 eq.) of copper(I) -chloride. Afterwards, the reaction mixture was warmed up to RT. 1 hour later, the mixture was poured into crashed ice and extracted three times with AcOEt; the organic phases were washed with water, dried over MgSO4, filtered and evaporated i.V. to yield 2.81 g of the title compound as brown oil.MS: 237.0 (M)+, 1 Cl.
 

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