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Chemical Structure| 927802-17-3 Chemical Structure| 927802-17-3

Structure of 927802-17-3

Chemical Structure| 927802-17-3

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Product Details of [ 927802-17-3 ]

CAS No. :927802-17-3
Formula : C9H10N2O2
M.W : 178.19
SMILES Code : NC1=NOC2=CC=CC(OCC)=C12
MDL No. :MFCD09055057

Safety of [ 927802-17-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H317-H319
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 927802-17-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 927802-17-3 ]

[ 927802-17-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 546-88-3 ]
  • [ 119584-73-5 ]
  • [ 927802-17-3 ]
YieldReaction ConditionsOperation in experiment
15% b) 4-Ethoxybenzo[d]isoxazol-3-amine I53 To a solution of acetohydroxamic acid (2.18 g, 29 mmol) in DMF (40 ml.) at 0 C under N2was added t-BuOK (3.26 g, 29 mmol) and the mixture was stirred at RT for 1 h. 2-Ethoxy-6-fluorobenzonitrile I52 (1.6 g, 9.7 mmol) was then added and the mixture was stirred at RT overnight. The mixture was diluted with DCM (80 ml_), washed with water (60 ml. x 4), dried over Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by column chromatography (Pet.ether/EtOAc = 5/1) to give the title compound (240 mg, 15%) as a white solid. LCMS- E: Rt5.05 min; m/z 179.0 [M+H]+.
 

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