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Chemical Structure| 923591-34-8 Chemical Structure| 923591-34-8

Structure of 923591-34-8

Chemical Structure| 923591-34-8

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Product Details of [ 923591-34-8 ]

CAS No. :923591-34-8
Formula : C14H24N2O5S
M.W : 332.42
SMILES Code : O=C(OC(C)(C)C)N[C@@]1(C(NS(=O)(C2CC2)=O)=O)[C@H](CC)C1

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Application In Synthesis of [ 923591-34-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 923591-34-8 ]

[ 923591-34-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 154350-29-5 ]
  • [ 159700-60-4 ]
  • [ 923591-34-8 ]
YieldReaction ConditionsOperation in experiment
73% Compound 73; Compound 73 was prepared as described herein; Step 1: Synthesis of tert-butyl (1R,2S )-1-(cyclopropylsulfonylcarbamoyl)-2- ethylcyclopropylcarbamate; (1R,2S)-1-(tert-butoxycarbonyl)-2-ethylcyclopropanecarboxylic acid (0.5 g, 2.18 mmol) was dissolved in THF (20 mL), followed by addition of CDI (390 mg, 2.41 mmol) in one portion at rt. The reaction was stirred in a 60 C sandbath for 4 h, cooled to it, and <strong>[154350-29-5]cyclopropanesulfonamide</strong> (292 mg, 2.41 mmol) and DBU (366 mg, 2.41 mmol) were added. The reaction was stirred at rt for overnight. The reaction was then diluted with <n="153"/>EtOAc (30 mL) and washed with 1 N HCl (2 x 15 raL), water (10 mL), brine (10 mL), and dried (Na2SO4), giving tert-butyl (lJ?,2JR)-1-(cyclopropylsulfonylcarbamoyl)-2- ethylcyclopropylcarbamate(0.53 g, 73% yield) as a white solid after removal of solvent. This crude product was directly used for the next without further purification.
  • 2
  • [ 159622-10-3 ]
  • [ 923591-34-8 ]
 

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