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Chemical Structure| 915230-14-7 Chemical Structure| 915230-14-7

Structure of 915230-14-7

Chemical Structure| 915230-14-7

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Product Details of [ 915230-14-7 ]

CAS No. :915230-14-7
Formula : C8H10F5NO4
M.W : 279.16
SMILES Code : O=C([C@H]1NCC(F)(F)C1)OC.O=C(O)C(F)(F)F
MDL No. :MFCD22415243

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Application In Synthesis of [ 915230-14-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 915230-14-7 ]

[ 915230-14-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 76-05-1 ]
  • [ 203866-17-5 ]
  • [ 915230-14-7 ]
YieldReaction ConditionsOperation in experiment
77% for 0.5h; (S)-4,4-Difluoro-N-Boc-pyrrolidine-2-carboxylic acid methyl ester (1.08 g, 4.07 mmol) was dissolved in TFA (5 mL) and stirred under N2 for 30 min. The solvent was removed under vacuum and the residue dissolved in MeOH5 loaded onto an SCX ion exchange column, washed with MeOH and DCM then eluted with 5% NH3 in MeOH. The solvent was removed to give the product as a pale brown oil. Yield: 77%; LCMS (RT): 0.63 min (Method A); MS (ES+) gave m/z: 166 (MH+).
 

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