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Chemical Structure| 91493-94-6 Chemical Structure| 91493-94-6

Structure of 91493-94-6

Chemical Structure| 91493-94-6

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Product Details of [ 91493-94-6 ]

CAS No. :91493-94-6
Formula : C12H9N3O
M.W : 211.22
SMILES Code : OC1=C2C(NC=C2)=NC(C3=CC=CC=C3)=N1
MDL No. :MFCD09746280

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Application In Synthesis of [ 91493-94-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 91493-94-6 ]

[ 91493-94-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 52133-67-2 ]
  • [ 1670-14-0 ]
  • [ 91493-94-6 ]
YieldReaction ConditionsOperation in experiment
Benzamidine hydrochloride (4.0 g, 0.25 mol) was dissolved in 64 ml of ethanol. To this 8.0 ml of a 25 wt percent solution of sodium methoxide was added. Reaction was then stirred at room temperature for 5 hrs, and filtered. Filtrate was then added to ethyl-2-cyano-4, 4-diethoxybutyrate (4.80 g, 0.21 mol). This solution was refluxed for 5 hrs.Half of solvent was removed under reduced pressure, then 80 ml of ice water was added, and the pH was adjusted to 7 with acetic acid. Material was then chilled for 6 hrs and product was isolated by vacuum filtration
 

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