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Chemical Structure| 913835-63-9 Chemical Structure| 913835-63-9

Structure of 913835-63-9

Chemical Structure| 913835-63-9

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Product Details of [ 913835-63-9 ]

CAS No. :913835-63-9
Formula : C7H7BN2O2
M.W : 161.95
SMILES Code : OB(C1=CN2C(C=C1)=NC=C2)O
MDL No. :MFCD06739225
InChI Key :IPJIKGJKMCILGV-UHFFFAOYSA-N
Pubchem ID :44119340

Safety of [ 913835-63-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 913835-63-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 913835-63-9 ]

[ 913835-63-9 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 6188-23-4 ]
  • [ 73183-34-3 ]
  • [ 913835-63-9 ]
YieldReaction ConditionsOperation in experiment
72% With tris-(dibenzylideneacetone)dipalladium(0); sodium acetate; tricyclohexylphosphine In 1,4-dioxane at 115 - 120℃; for 24 h; 20.0 g of compound vii (0.102 mol), 38.7 g of bis(pinacolato)diboron (0.152 mol), 2.85 g of tricyclohexyl phosphine (0.010 mol), 4.65 g of tris(dibenzylideneacetone)dipalladium (0.005 mol) and 25.0 sodium acetate were added to 200ml 1,4-dioxane, heated to 115 ~ 120 , incubation reaction 24h, cooling to room temperature, adding purified water 200ml. Extracted twice with 200 ml of ethyl acetate, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give a reddish brown solid. The solid was added to 30 ml of t-butyl methyl ether, stirred for 2 h. A yellowish solid, i.e. 9-azoindole-5-boronic acid (compound vi), was filtered off and weighed 11.8 g in a yield of 72.0percent.
References: [1] Patent: CN106349246, 2017, A, . Location in patent: Paragraph 0023; 0026; 27.
 

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