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Chemical Structure| 913631-66-0 Chemical Structure| 913631-66-0
Chemical Structure| 913631-66-0

tert-Butyl ((1S,2R)-2-hydroxycyclopentyl)carbamate

CAS No.: 913631-66-0

4.5 *For Research Use Only !

Cat. No.: A502422 Purity: 95%

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Product Details of [ 913631-66-0 ]

CAS No. :913631-66-0
Formula : C10H19NO3
M.W : 201.26
SMILES Code : O=C(OC(C)(C)C)N[C@@H]1[C@H](O)CCC1
MDL No. :MFCD13195019
InChI Key :CGZQRJSADXRRKN-JGVFFNPUSA-N
Pubchem ID :51416200

Safety of [ 913631-66-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 913631-66-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 913631-66-0 ]

[ 913631-66-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 24424-99-5 ]
  • [ 225791-13-9 ]
  • [ 913631-66-0 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In dichloromethane; at 16℃; for 12h; To a solution of (1S, 2R)-2-aminocyclopentanol, hydrochloride (2 g, 14.53 mmol, 1 eq) in DCM (20 mL) was added TEA (4.41 g, 43.60 mmol, 6.07 mL, 3 eq) and Boc2O (3.17 g, 14.53 mmol, 3.34 mL, 1 eq). The mixture was stirred at l6C for 12 h. It was concentrated under reduced pressure to remove DCM. The residue was diluted with water 50 mL, adjusted pH to 7 by added HC1 (1 M), and then extracted with EtOAc (30 mLx3). The combined organic layers were washed with brine (50 mL), dried over Na2S04, filtered and concentrated under reduced pressure to afford the title compound (2.5 g, crude) as a colorless oil whcih was used directly into the next step without purification.
 

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