Home Cart Sign in  
Chemical Structure| 885665-26-9 Chemical Structure| 885665-26-9

Structure of 885665-26-9

Chemical Structure| 885665-26-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 885665-26-9 ]

CAS No. :885665-26-9
Formula : C48H35N3
M.W : 653.81
SMILES Code : C1(NC2=C3C=C(C4=CC=C(N(C5=CC=CC=C5)C6=CC=CC=C6)C=C4)C=C2)=C3C=C(C7=CC=C(N(C8=CC=CC=C8)C9=CC=CC=C9)C=C7)C=C1

Safety of [ 885665-26-9 ]

Application In Synthesis of [ 885665-26-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 885665-26-9 ]

[ 885665-26-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 267221-88-5 ]
  • [ 6825-20-3 ]
  • [ 885665-26-9 ]
YieldReaction ConditionsOperation in experiment
88% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; water; for 48h;Inert atmosphere; Reflux; 3,6-dibromocarbazole (1.97 g, 6.05 mmol) under closed, argon-containing conditionsN,N-diphenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)amine (5.63 g, 15.15 mmol),The catalyst tetrakistriphenylphosphine palladium (Pd(PPh3)4) (0.70 g, 0.61 mmol) was dissolved in tetrahydrofuran (80 ml).After heating to reflux, the aqueous K2CO3 solution (2 mol/L, 30.5 ml, 60.5 mmol) was added to the reaction system, and the reaction was carried out under reflux for 48 hours.The solvent was distilled off and the column chromatography was carried out. The eluent was petroleum ether/dichloromethane = 4/1 (volume ratio).It was then recrystallized from tetrahydrofuran/ethanol to give a white powder (yield: 88%).
80% With tetrabutylammomium bromide; sodium carbonate; triphenylphosphine; In toluene; at 110℃; for 18h;Inert atmosphere; Under argon atmosphere,3,6-dibromocarbazole (5 g, 915.38 mmol) andTriphenylamine borate (17.14 g,46.15 mmol) was added to two vials,Then add 100ml toluene to complete dissolution,Sodium carbonate (8.15 g,76.92 mmol),Tetrabutylammonium bromide (312.01 mg, 967.86 mol)withTetraphenylphenylphosphine (355.56 mg,307.69umol),The reaction was carried out at 110 C for 18 h.The reaction mixture was poured into water,Extracted with ethyl acetate,After the organic layer was completely washed with brine,Add anhydrous magnesium sulfate dry.After the solution was concentrated,Purification by silica gel column chromatography (eluent selection petroleum ether / dichloromethane = 6/1, v / v) gave a white solid in 80% yield.
80% With tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide; sodium carbonate; In toluene; at 110℃; for 18h;Inert atmosphere; Under argon atmosphere, 3,6-dibromocarbazole (5 g, 915.38 mmol) and triphenylamine borate(17.14 g, 46.15 mmol) was added to two vials and 100 ml of toluene was added for complete dissolution,Sodium carbonate (8.15 g, 76.92 mmol) was added,Tetrabutylammonium bromide (312.01 mg, 967.86 mol) andTetraphenylphenyl phosphatePalladium (355.56 mg, 307.69 mol)The reaction was carried out at 110 C for 18 h.The reaction mixture was poured into water, extracted with ethyl acetate, and the organic layer was completely washed with brine,Add anhydrous magnesium sulfate dry. The solution was concentrated and purified by silica gel column chromatography (eluent selection of petroleum ether / bisMethyl chloride = 6/1, v / v) to give a white solid in 80% yield.
80% With tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide; sodium carbonate; In toluene; at 110℃; for 18h;Inert atmosphere; Under argon atmosphere,A mixture of 3,6-dibromocarbazole (5 g, 915.38 mmol)And triphenylamine borate (17.14 g, 46.15 mmol) were added to two vials,Then add 100ml toluene to complete dissolution,Sodium carbonate (8.15 g, 76.92 mmol) was added,Tetrabutylammonium bromide (312.01 mg, 967.86 mol)And tetraphenylphenylphosphine (355.56 mg, 307.69 mol)The reaction was carried out at 110 C for 18 h.The reaction mixture was poured into water,Extracted with ethyl acetate, and the organic layer was completely washed with brine,Add anhydrous magnesium sulfate dry. After the solution was concentrated,Purification by silica gel column chromatography (eluent selection of petroleum ether / dichloromethane = 6/1, v / v)The final white solid was obtained in 80% yield.
80% With tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide; sodium carbonate; In toluene; at 110℃; for 18h;Inert atmosphere; Under an argon atmosphere, 3,6-dibromocarbazole (5 g, 915.38 mmol) and triphenylamine borate (17.14 g,46.15 mmol) was added to two vials and 100 ml of toluene was added for complete dissolution followed by addition of sodium carbonate (8.15 g,(35.01 mg, 967.86 mol) and tetraphenylphenylphosphine (355.56 mg, 307.69 mol) were reacted at 110 C for 18 h. The reaction mixture was poured into water,After extraction with ethyl acetate, the organic layer was washed thoroughly with brine and dried over anhydrous magnesium sulfate. The solution was concentrated and purified by silica gel column chromatography (eluent selection of petroleum ether / diMethyl chloride = 6/1, v / v) to give a white solid in 80% yield.
80% With tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide; sodium carbonate; In toluene; at 110℃; for 18h;Inert atmosphere; Under argon atmosphere,A mixture of 3,6-dibromocarbazole (5 g, 915.38 mmol)And triphenylamine borate (17.14 g, 46.15 mmol)Add to two bottles,Then add 100ml toluene to complete dissolution,Sodium carbonate (8.15 g, 76.92 mmol) was added,Tetrabutylammonium bromide (312.01 mg, 967.86 mol)And tetrakis triphenylphosphine palladium (355.56mg, 307.69umol),The reaction was carried out at 110 C for 18 h.The reaction mixture was poured into water,Extracted with ethyl acetate,After the organic layer was completely washed with brine,Add anhydrous magnesium sulfate dry.After the solution was concentrated,Purification by silica gel column chromatography (eluent selection petroleum ether / dichloromethane = 6/1, v / v)The final white solid was obtained in 80% yield.
80% With tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide; sodium carbonate; In toluene; at 110℃; for 18h;Inert atmosphere; In the argon atmosphere, will be 3, 6 - dibromo carbazole (5 g, 915.38 mmol) and triphenylamine borate (17.14 g, 46 . 15 mmol) is added to the two bottles in, add 100 ml toluene completely dissolved, add the sodium carbonate (8.15 g, 76 . 92 mmol), tetrabutyl ammonium bromide (312.01 mg, 967 . 86 umol) and four triphenyl phosphate palladium (355.56 mg, 307 . 69 umol), in 110 C reaction under 18 h; the reaction mixture is poured into water, extracted with ethyl acetate, the organic layer using salt water completely after washing, add anhydrous magnesium sulfate drying; solution after concentration, purification with silica gel column chromatography (elution agent selected petroleum ether/dichloromethane=6/1, v/v), at the end of the white solid, yield 80%.
80% With tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide; sodium carbonate; In toluene; at 110℃; for 18h;Inert atmosphere; Under argon atmosphere, 3,6-dibromocarbazole (5 g, 915.38 mmol) and triphenylamine boronate (17.14 g, 46.15 mmol) were added to the two-necked flask, and 100 ml of toluene was further added for complete dissolution Followed by sodium carbonate (8.15 g, 76.92 mmol), tetrabutylammonium bromide (312.01 mg, 967.86 umol) and palladium tetrakistriphenylphosphine (355.56 mg, 307.69 mol) and reacted at 110 C for 18 h. The reaction mixture was poured into water and extracted with ethyl acetate. The organic layer was washed thoroughly with brine and then dried over anhydrous magnesium sulfate. The solution was concentrated and purified by silica gel column chromatography (eluent petroleum ether / methylene chloride = 6/1, v / v) to give a white solid in a yield of 80%.
80% With tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide; sodium carbonate; In toluene; at 110℃; for 18h; Under an argon atmosphere,Add 3,6-dibromocarbazole (5g, 915.38mmol) and triphenylamine boronate (17.14g, 46.15mmol) into two-necked flask and add 100ml of toluene for complete dissolution. Add sodium carbonate (8.15g, 76.92 mmol), tetrabutylammonium bromide (312.01 mg, 967.86 umol) and palladium tetrakistriphenylphosphine (355.56 mg, 307.69 umol) were added and reacted at 110 C for 18 h; the reaction mixture was poured into water and extracted with ethyl acetate The organic layer was washed thoroughly with brine and dried over anhydrous magnesium sulfate. After the solution was concentrated, the residue was purified by silica gel column chromatography (eluting with petroleum ether / methylene chloride = 6/1, v / v) A white solid was obtained in 80% yield.
80% With tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide; sodium carbonate; In toluene; at 110℃; for 18h;Inert atmosphere; Under an argon atmosphere, 3,6-dibromocarbazole (5 g, 915.38 mmol) and triphenylamine boronate (17.14 g,46.15 mmol) was added to two bottles, 100 ml of toluene was added for complete dissolution, sodium carbonate (8.15 g, 76.92 mmol), tetrabutylammonium bromide (312.01 mg, 967 · 86 μmol) and tetraphenylphosphine palladium (355.56 mg, 307.69 umol) was reacted at 110 C. for 18 h; the reaction mixture was poured into water and extracted with ethyl acetate. The organic layer was completely washed with brine and dried over anhydrous magnesium sulfate; the solution was concentrated. After purification by silica gel column chromatography (eluent selected petroleum ether/dichloromethane = 6/1, v/v), a white solid was finally obtained with a yield of 80%.

 

Historical Records