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Chemical Structure| 875798-79-1 Chemical Structure| 875798-79-1
Chemical Structure| 875798-79-1

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1-Boc-3-(4-Aminophenyl)piperidine

CAS No.: 875798-79-1

4.5 *For Research Use Only !

Cat. No.: A379745 Purity: 98%

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Product Details of [ 875798-79-1 ]

CAS No. :875798-79-1
Formula : C16H24N2O2
M.W : 276.37
SMILES Code : CC(C)(C)OC(=O)N1CCCC(C1)C1=CC=C(N)C=C1
MDL No. :MFCD05861561
InChI Key :SWUANUQBXJNXGP-UHFFFAOYSA-N
Pubchem ID :44607626

Safety of [ 875798-79-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis [ 875798-79-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 875798-79-1 ]

[ 875798-79-1 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 34619-03-9 ]
  • [ 19733-56-3 ]
  • [ 875798-79-1 ]
  • 2
  • [ 19733-56-3 ]
  • [ 875798-79-1 ]
  • 3
  • [ 24424-99-5 ]
  • [ 19733-56-3 ]
  • [ 875798-79-1 ]
YieldReaction ConditionsOperation in experiment
2.67 g With sodium hydroxide; In methanol; water; at 0 - 20℃; A mixture of 4-(piperidin-3-yl) aniline (Compound 16) (2.0 g) in methanol (10 mL) and water (5 mL) in a reactor was cooled to 0-5C. NaOH (1.81 g) and Boc anhydride (2.59 g) was slowly charged with stirring to the reaction mixture. The reaction mass was stirred at 5-10C and then allowed to warm up to 20C until HPLC/TLC analysis indicated completion of reaction. The product was filtered, washed with water (6 mL) and methanol (2 mL) mixture. The solid was dried under vacuum at 50-55C to afford the titled compound (Yield: 2.67 g; HPLC Purity: > 95.0%).
 

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