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Chemical Structure| 868594-48-3 Chemical Structure| 868594-48-3
Chemical Structure| 868594-48-3

Benzyl-PEG9-alcohol

CAS No.: 868594-48-3

Benzyl-PEG9-alcohol is a PEG-based PROTAC linker used for synthesizing PROTAC molecules.

Synonyms: Benzyl-PEG9-alcohol

4.5 *For Research Use Only !

Cat. No.: A173556 Purity: 98%

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Product Details of [ 868594-48-3 ]

CAS No. :868594-48-3
Formula : C25H44O10
M.W : 504.61
SMILES Code : OCCOCCOCCOCCOCCOCCOCCOCCOCCOCC1=CC=CC=C1
Synonyms :
Benzyl-PEG9-alcohol
MDL No. :MFCD24682797
InChI Key :GMSWKGHIOXBMJE-UHFFFAOYSA-N
Pubchem ID :68687189

Safety of [ 868594-48-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis [ 868594-48-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 868594-48-3 ]

[ 868594-48-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3386-18-3 ]
  • [ 100-44-7 ]
  • [ 868594-48-3 ]
YieldReaction ConditionsOperation in experiment
31% With sodium hydroxide; In tetrahydrofuran; at 20℃; for 5h; Nonaethylene glycol (2 g, 4.8 mmol, 1 eq, Leap Labchem)Benzyl chloride (0.417 ml, 3.6 mmol, 0.75 eq) and sodium hydroxide (230 mg, 5.76 mmol, 1.2eq) were placed in a round flask, dissolved in 20 ml of tetrahydrofuran and stirred at room temperature for 5 hours.Thereafter, the mixture was extracted with dichloromethane and distilled water, and then the dichloromethane layer was dried with magnesium sulfate, filtered, and filtered to obtain transparent liquid particles through distillation under reduced pressure (0.741 g, 31%)
 

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