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Chemical Structure| 859850-63-8 Chemical Structure| 859850-63-8

Structure of 859850-63-8

Chemical Structure| 859850-63-8

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Product Details of [ 859850-63-8 ]

CAS No. :859850-63-8
Formula : C7H12N2O
M.W : 140.18
SMILES Code : CNCC1=C(C)OC(C)=N1
MDL No. :MFCD08271884

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Application In Synthesis of [ 859850-63-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 859850-63-8 ]

[ 859850-63-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 92901-88-7 ]
  • [ 74-89-5 ]
  • [ 859850-63-8 ]
YieldReaction ConditionsOperation in experiment
Example 1.1.10: l-( 2,5-dimethyloxazol-4-yl ) -N-methylmethanamine[0287] Ti(0,PR)4 (1. 08 mL, 3.69 mmoles) was added with stirring to MeNH2 ( 4.3 mL, 2.0 M in MeOH, 8.5 mmoles ) at 0 C under Ar. After 15 min the aldehyde ( 360 mg, 2. 83 mmoles) was added, and the reaction was stirred for 2-3 h. NaBH4 (139 mg, 3.69 mmoles) was added in batches, and the reaction was stirred at 0 C to RT overnight. The solvent was removed via rotary evaporation. The residue was diluted with water/CH2Cl2. A white ppt formed and was removed via filtration through Celite. The layers were separated. The aqueous layer was extracted with CH2C12 (x3) and the combined organics were dried over Na2S04. The inorganics were filtered off, and the solvent was removed via rotary evaporation to give 300 mg of l-(2,5-dimethyloxazol-4-yl)-N-methylmethanamine.
 

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