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Chemical Structure| 858597-92-9 Chemical Structure| 858597-92-9

Structure of 858597-92-9

Chemical Structure| 858597-92-9

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Product Details of [ 858597-92-9 ]

CAS No. :858597-92-9
Formula : C14H13NO2
M.W : 227.26
SMILES Code : CC(C1=NC=C(OCC2=CC=CC=C2)C=C1)=O
MDL No. :MFCD10697707

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Application In Synthesis of [ 858597-92-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 858597-92-9 ]

[ 858597-92-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 78760-60-8 ]
  • [ 75-16-1 ]
  • [ 858597-92-9 ]
YieldReaction ConditionsOperation in experiment
90% In tetrahydrofuran; for 3h;Inert atmosphere; Reflux; To a reflux condenser 20mL round bottom flask was added 5mL anhydrous tetrahydrofuran solution, 0.5mmol <strong>[78760-60-8]5-benzyloxy-2-cyanopyridine</strong>,The mixture was stirred and replaced with nitrogen for three times. 1.5 mmol of methylmagnesium bromide was slowly added under the protection of nitrogen at room temperature. The whole system was heated to reflux and reacted for 3 hours.The whole reaction was poured into ice-water and extracted three times with dichloromethane, each time 20 mL, concentrated to give a white solid product, 102 mg, yield 90%.
 

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