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Chemical Structure| 840506-29-8 Chemical Structure| 840506-29-8
Chemical Structure| 840506-29-8

Acelarin

CAS No.: 840506-29-8

Acelarin is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine.

Synonyms: NUC-1031; CPF-31; GTPL7389

4.5 *For Research Use Only !

Cat. No.: A426804 Purity: 99%

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Product Details of Acelarin

CAS No. :840506-29-8
Formula : C25H27F2N4O8P
M.W : 580.47
SMILES Code : C[C@H](NP(OC1=CC=CC=C1)(OC[C@H]2O[C@@H](N3C=CC(N)=NC3=O)C(F)(F)[C@@H]2O)=O)C(OCC4=CC=CC=C4)=O
Synonyms :
NUC-1031; CPF-31; GTPL7389
MDL No. :MFCD27987942
InChI Key :NHTKGYOMICWFQZ-KKQYNPQSSA-N
Pubchem ID :11169170

Safety of Acelarin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of Acelarin

DNA

Isoform Comparison

Biological Activity

Target
  • DNA synthesis

    DNA synthesis, EC50:0.2 nM

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01621854 Cancer PHASE1 COMPLETED 2025-06-15 NIHR/Wellcome Trust Imperial C... More >>RF, London, Hammersmith, W12 0HS, United Kingdom Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.72mL

0.34mL

0.17mL

8.61mL

1.72mL

0.86mL

17.23mL

3.45mL

1.72mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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