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Chemical Structure| 834861-78-8 Chemical Structure| 834861-78-8

Structure of 834861-78-8

Chemical Structure| 834861-78-8

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Product Details of [ 834861-78-8 ]

CAS No. :834861-78-8
Formula : C8H8BrNS
M.W : 230.12
SMILES Code : S=C(N)CC1=CC=CC(Br)=C1

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Application In Synthesis of [ 834861-78-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 834861-78-8 ]

[ 834861-78-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 60312-83-6 ]
  • [ 834861-78-8 ]
YieldReaction ConditionsOperation in experiment
With Lawessons reagent; In tetrahydrofuran; at 80℃; for 12h; General procedure: Toan oven-dried round bottom flask charged with 2-(4-chlorophenyl)acetamide57(196 mg, 1.16 mmol, 1.0 equiv.),and THF (10 mL) was added Lawesson reagent (518 mg, 1.28mmol, 1.1 equiv.).The reaction mixture was allowed to stir at 80 for 12 hr.The reaction was quenched with saturated NaHCO3solution and extracted withEtOAc. The combined organic layer was washed with brine, dried overMgSO4,filtered,and concentrated under reduced pressure. The residue was purified by column chromatography (n-hexanes/EtOAc)to afford the corresponding thioamide.
 

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