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Chemical Structure| 827322-77-0 Chemical Structure| 827322-77-0

Structure of 827322-77-0

Chemical Structure| 827322-77-0

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Product Details of [ 827322-77-0 ]

CAS No. :827322-77-0
Formula : C6H2F6O3S2
M.W : 300.20
SMILES Code : O=S(C(F)(F)F)(OC1=CSC(C(F)(F)F)=C1)=O

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Application In Synthesis of [ 827322-77-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 827322-77-0 ]

[ 827322-77-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 358-23-6 ]
  • [ 217959-45-0 ]
  • [ 827322-77-0 ]
YieldReaction ConditionsOperation in experiment
92% With pyridine; In dichloromethane; at 0 - 20℃; for 3.0h; TRIFLUOROMETHANESULFONIC anhydride (12 ML, 92. 8 mmol, 2 eq. ) was added drop- wise to a 0 C solution of <strong>[217959-45-0]3-hydroxy-5-trifluoromethylthiophene</strong> (7. 8 g, 46.4 mmol, prepared as in Synthesis 2000 get reference), pyridine (7.4 M 1, 9 2. 8 M MOL, 2 eq. ), and DICHLOROMETHANE (230 ML). The mixture was allowed to warm to rt and maintained for 3 h. At this time, the solution was diluted with DICHLOROMETHANE (200 ML), washed with brine (100 ML), 1 M HCI (100 ml), and brine (100 ML). The organic layer was dried (MGS04), filtered, and concentrated to yield 1 as a reddish-orange oil (12. 8 g, 92 %).
 

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