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Chemical Structure| 811450-82-5 Chemical Structure| 811450-82-5

Structure of 811450-82-5

Chemical Structure| 811450-82-5

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Product Details of [ 811450-82-5 ]

CAS No. :811450-82-5
Formula : C10H11ClN2O4
M.W : 258.66
SMILES Code : O=C(NC1=CC=C([N+]([O-])=O)C=C1)COCCCl
MDL No. :MFCD18379274

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Application In Synthesis of [ 811450-82-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 811450-82-5 ]

[ 811450-82-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 14869-41-1 ]
  • [ 100-01-6 ]
  • [ 811450-82-5 ]
YieldReaction ConditionsOperation in experiment
83% With phenylboronic acid; In toluene; at 110 - 111℃;Dean-Stark; Reflux; 90 ml toluene, lO.OOg <strong>[14869-41-1]2-<strong>[14869-41-1](2-chloroethoxy)acetic acid</strong></strong> (X) oily extract obtained from one of the previous examples, 8.3 Ig 4-nitro-aniine and l .84g phenyl -boronic acid are measured into a 125 ml volume sulfonating flask equipped with a Dean-Stark attachment, a condenser and thermometer. The mixture is heated to the reflux temperature (1 10- 1 11 C), the reaction is checked by a TLC method. After the end of the reaction the mixture is cooled back, 1.00 ml ethylene-glycol is added. Then the mixture is heated again to the temperature of reflux, then it is refluxed for another half an hour. Then the mixture is cooled to a temperature of 0-5C. The suspension is filtered and washed with toluene. The filtrate is dried to a constant mass. The mass of the obtained pastel yellow powder: 12.98g, yield: 83%
 

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