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Chemical Structure| 80109-83-7 Chemical Structure| 80109-83-7

Structure of 80109-83-7

Chemical Structure| 80109-83-7

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Product Details of [ 80109-83-7 ]

CAS No. :80109-83-7
Formula : C12H11NO2
M.W : 201.22
SMILES Code : O=C(C1=NC2=CC=CC=C2C(C)=C1)OC
MDL No. :MFCD03413688

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Application In Synthesis of [ 80109-83-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 80109-83-7 ]

[ 80109-83-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 6773-29-1 ]
  • [ 52562-19-3 ]
  • [ 80109-83-7 ]
YieldReaction ConditionsOperation in experiment
50% With dirhodium tetraacetate; copper diacetate; sodium carbonate; In 1,2-dichloro-ethane; at 100℃; for 16h;Sealed tube; General procedure: To a 25mL tube containing a magnetic stir bar, was added 2-vinylanilines 1 (0.2mmol), Rh2(OAc)4 (0.01mmol, 5mol%), Cu(OAc)2 (0.4mmol, 2.0 equiv), Na2CO3 (0.4mmol, 2.0 equiv), 1,2-DCE (2mL), and α-diazocarbonyl compounds 2 (0.4mmol, 2 equiv). The resulting mixture was stirred at 100C in air in sealed tube for 16h. After being cooled to room temperature, the reaction was monitored by TLC and the solvent was evaporated under reduced pressure. Purification was carried out by column chromatography using a mixture of ethyl acetate and petroleum ether (1:10 to 1:20) as eluent to obtain the desired product 3.
  • 2
  • [ 52562-19-3 ]
  • [ 762-42-5 ]
  • [ 80109-83-7 ]
 

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