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Chemical Structure| 773873-98-6 Chemical Structure| 773873-98-6

Structure of 773873-98-6

Chemical Structure| 773873-98-6

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Product Details of [ 773873-98-6 ]

CAS No. :773873-98-6
Formula : C9H8F2O2
M.W : 186.16
SMILES Code : O=C(OC)C1=C(F)C=CC(C)=C1F
MDL No. :MFCD06203779

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Application In Synthesis of [ 773873-98-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 773873-98-6 ]

[ 773873-98-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 67-56-1 ]
  • [ 32890-88-3 ]
  • [ 773873-98-6 ]
YieldReaction ConditionsOperation in experiment
86% With thionyl chloride; at 0℃;Heating / reflux; To a 0 "C solution of 2,6-difluoro-3- methylbenzoic acid (10.0 g, 58.1 mrnol, 1.0 equiv) in dry methanol (100 mL) was added dropwise thionyl chloride (4.64 mL, 63.9 mmol, 1.1 equiv). The resulting solution was refluxed overnight. After the reaction mixture was allowed to cool to room temperature, the solvent was removed in vacuo. The product was dissolved in ethyl acetate and washed with aq. satd. NaHCO3. The EtOAc layer was dried over sodium sulfate, filtered and concentrated in vacuo to provide the desired ester (9.35 g, 86%).
 

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