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Chemical Structure| 7515-41-5 Chemical Structure| 7515-41-5

Structure of 7515-41-5

Chemical Structure| 7515-41-5

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Product Details of [ 7515-41-5 ]

CAS No. :7515-41-5
Formula : C10H11Br
M.W : 211.10
SMILES Code : BrCC/C=C/C1=CC=CC=C1
MDL No. :MFCD11936563

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Application In Synthesis of [ 7515-41-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7515-41-5 ]

[ 7515-41-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1007-03-0 ]
  • [ 7515-41-5 ]
YieldReaction ConditionsOperation in experiment
70% With ethyl 2,2-dibromoacetoacetate; triphenylphosphine; In dichloromethane; at 20℃; for 0.833333h; General procedure: Ethyl α,α-dibromoacetoacetate 2a (0.41 mmol, 1.2 equiv), alcohols 1a-1s (0.34 mmol, 1.0 equiv) and Ph3P (0.68 mmol, 2.0 equiv) were added under ambient temperature to 3 mL of DCE in air. After stirred at room temperature for appropriate time (monitored by TLC), the reaction was quenched by addition of H2O (3 mL) and then extracted with ethyl acetate (3×3 mL). The combined organic layer was washed with brine, dried over Na2SO4, and concentrated. The crude product was purified by column chromatography on silica gel with petroleum ether or mixture of petroleum ether and ethyl acetate as eluent to afford the corresponding products 3a-3s.
 

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