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Chemical Structure| 74702-94-6 Chemical Structure| 74702-94-6

Structure of 74702-94-6

Chemical Structure| 74702-94-6

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Product Details of [ 74702-94-6 ]

CAS No. :74702-94-6
Formula : C10H15NO
M.W : 165.23
SMILES Code : CC(N)(C1=CC=CC=C1OC)C
MDL No. :MFCD09903845

Safety of [ 74702-94-6 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:2735
Packing Group:

Application In Synthesis of [ 74702-94-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 74702-94-6 ]

[ 74702-94-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6609-56-9 ]
  • [ 75-16-1 ]
  • [ 74702-94-6 ]
YieldReaction ConditionsOperation in experiment
(1) 2-Methoxybenzonitrile (6 g) was dissolved in diethyl ether (140 ml), a 3 M solution of methylmagnesium bromide in diethyl ether (45 ml) was added to the solution, and the resulting mixture was stirred at room temperature for 1 hour. Titanium tetraisopropoxide (13.1 ml) was added to the reaction mixture, and the resulting mixture was stirred for 4 hours under reflux by heating. 10% Aqueous sodium hydroxide (160 ml) and ethyl acetate (160 ml) were added to the reaction mixture, and the resulting mixture was stirred at room temperature for 1 hour. The reaction mixture was filtered through Celite, and then the layers of the filtrate were separated. The aqueous layer was extracted with chloroform, and the organic layer was dried over anhydrous magnesium sulfate, and filtered. The filtrate was concentrated under reduced pressure, and the resulting residue was purified by silica gel column chromatography (chloroform:methanol:28% aqueous ammonia = 40:1:0.1 to 10:1:0.1) to obtain a dimethylamine compound (2.76 g).
 

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