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Chemical Structure| 739366-20-2 Chemical Structure| 739366-20-2
Chemical Structure| 739366-20-2

*Storage: Keep in dark place,Inert atmosphere,2-8°C.

Anagliptin

CAS No.: 739366-20-2

Anagliptin is an orally active, selective DPP-4 inhibitor with an IC50 of 3.8 nM, exhibiting relatively weaker inhibition on DPP-8 and DPP-9.

Synonyms: SK-0403

4.5 *For Research Use Only !

Cat. No.: A636346 Purity: 98+%

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Product Details of [ Anagliptin ]

CAS No. :739366-20-2
Formula : C19H25N7O2
M.W : 383.45
SMILES Code : O=C(C1=CN2C(N=C1)=CC(C)=N2)NCC(C)(NCC(N3[C@H](C#N)CCC3)=O)C
Synonyms :
SK-0403
MDL No. :N/A

Safety of [ Anagliptin ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01131091 Type 2 Diabetes Mellitus PHASE1 COMPLETED 2025-11-10 Orlando, Florida, United State... More >>s|Minneapolis, Minnesota, United States Less <<
NCT00532506 Type 2 Diabetes Mellitus PHASE2 COMPLETED - Fukuoka, Japan|Gifu, Japan|Gun... More >>ma, Japan|Hokkaido, Japan|Ibaragi, Japan|Kanagawa, Japan|Kumamoto, Japan|Oita, Japan|Okinawa, Japan|Tokyo, Japan Less <<
NCT04267601 Type 2 Diabetes Mellitus UNKNOWN 2021-09-30 The Catholic University of Kor... More >>ea, Bucheon ST. Mary's hopsital, Bucheon, 14647, Korea, Republic of Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.61mL

0.52mL

0.26mL

13.04mL

2.61mL

1.30mL

26.08mL

5.22mL

2.61mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline
Solubility: ≥ 2.5 mg/mL (6.52 mM); Clear solution
Protocol 2
Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (6.52 mM); Clear solution

References

 

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