Home Cart Sign in  
Chemical Structure| 73075-59-9 Chemical Structure| 73075-59-9

Structure of 73075-59-9

Chemical Structure| 73075-59-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 73075-59-9 ]

CAS No. :73075-59-9
Formula : C9H5Cl2N
M.W : 198.05
SMILES Code : ClC1=CC=C(Cl)C2=C1C=CN=C2
MDL No. :MFCD07644632
InChI Key :MIYJUWWLNPMRCD-UHFFFAOYSA-N
Pubchem ID :12595057

Safety of [ 73075-59-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P302+P352-P305+P351+P338

Application In Synthesis of [ 73075-59-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 73075-59-9 ]

[ 73075-59-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 119-65-3 ]
  • [ 5430-45-5 ]
  • [ 73075-59-9 ]
YieldReaction ConditionsOperation in experiment
45% With trichloroisocyanuric acid; sulfuric acid; at 0 - 10℃; for 24h; To mechanically stirred concd H 2 SO 4 (100 mL), isoquinoline (1; 12.9 g,0.1 mol, 1.0 equiv) was slowly added at 0 C. During intensive stirringTCCA (12.8 g, 55 mmol, 1.65 equiv) was then added in 4 portionswhile the reaction temperature was kept at 10 C. The mixture wasthen stirred at 10 C and followed by GC-MS. After 24 h the reactionmixture was poured onto crushed ice (ca. 200 g) and the precipitatewas filtered. The pH of the filtrate was adjusted to 2 with concd aqNH 3 solution with extensive cooling. The slurry was then filtered. Thefiltrate was extracted with toluene (6 × 75 mL) to remove the sideproduct, 5,8-dichloroisoquinoline (16). The aqueous phase was fur-ther basified with concd aq NH 3 solution until pH 6 was reached. Atthis point the precipitate was filtered, washed with H 2 O, and dried inair. Finally, the filtrate was recrystallized from methylcyclohexane toafford 15.Yield: 7.60 g (45%); mp 70-72 C.IR (ATR): 1580, 1489, 1371, 1267, 1204, 1140, 1065, 984, 822, 750,687, 628, 536 cm -1 .1 H NMR (400 MHz, CDCl 3 ): δ = 9.27 (s, 1 H), 8.64 (d, J = 6.0 Hz, 1 H),8.02 (d, J = 6.0 Hz, 1 H), 7.90 (d, J = 8.2 Hz, 1 H), 7.77 (d, J = 7.5 Hz, 1 H),7.53 (t, J = 7.8 Hz, 1 H).13 C NMR (100 MHz, CDCl 3 ): δ = 152.4, 143.9, 133.7, 131.0, 130.3,129.4, 127.3, 126.7, 116.9.
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 73075-59-9 ]

Chlorides

Chemical Structure| 34784-07-1

A144432 [34784-07-1]

8-Chloroisoquinoline

Similarity: 1.00

Chemical Structure| 5430-45-5

A493591 [5430-45-5]

5-Chloroisoquinoline

Similarity: 0.96

Chemical Structure| 635-27-8

A135791 [635-27-8]

5-Chloroquinoline

Similarity: 0.93

Chemical Structure| 611-35-8

A158683 [611-35-8]

4-Chloroquinoline

Similarity: 0.93

Chemical Structure| 86-98-6

A253994 [86-98-6]

4,7-Dichloroquinoline

Similarity: 0.93

Related Parent Nucleus of
[ 73075-59-9 ]

Isoquinolines

Chemical Structure| 34784-07-1

A144432 [34784-07-1]

8-Chloroisoquinoline

Similarity: 1.00

Chemical Structure| 5430-45-5

A493591 [5430-45-5]

5-Chloroisoquinoline

Similarity: 0.96

Chemical Structure| 61563-36-8

A162780 [61563-36-8]

7,8-Dichloroisoquinoline

Similarity: 0.93

Chemical Structure| 34784-06-0

A204259 [34784-06-0]

7-Chloroisoquinoline

Similarity: 0.93

Chemical Structure| 62882-02-4

A224530 [62882-02-4]

6-Chloroisoquinoline

Similarity: 0.93