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Chemical Structure| 726185-68-8 Chemical Structure| 726185-68-8

Structure of 726185-68-8

Chemical Structure| 726185-68-8

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Product Details of [ 726185-68-8 ]

CAS No. :726185-68-8
Formula : C9H13N3O2S
M.W : 227.28
SMILES Code : O=C(C1=CN=C(N2CCNCC2)S1)OC
MDL No. :MFCD07779206

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Application In Synthesis of [ 726185-68-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 726185-68-8 ]

[ 726185-68-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-85-0 ]
  • [ 72605-86-8 ]
  • [ 726185-68-8 ]
YieldReaction ConditionsOperation in experiment
34% In ethanol; for 3h;Heating / reflux; 10.0 g (116.09 mmol) of anhydrous piperazine were added to a solution of 4.2 g (23.647 mmol) of <strong>[72605-86-8]methyl 2-chlorothiazole-5-carboxylate</strong> in 5 ml of ethanol and refluxed for 3 hours. The reaction mixture was combined with saturated aqueous sodium hydrogen carbonate solution and exhaustively extracted with ethyl acetate. The combined organic extracts were washed thoroughly with water, dried over sodium sulphate and concentrated by evaporation in vacuo. 1.8 g (34% of theory) of colourless crystals were obtained, Rf 0.44 (EI D).
 

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