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[ CAS No. 71616-83-6 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 71616-83-6
Chemical Structure| 71616-83-6
Chemical Structure| 71616-83-6
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Product Details of [ 71616-83-6 ]

CAS No. :71616-83-6 MDL No. :MFCD22200103
Formula : C12H14O3 Boiling Point : -
Linear Structure Formula :- InChI Key :KTZOAXDUBMENLM-UHFFFAOYSA-N
M.W : 206.24 Pubchem ID :23143286
Synonyms :

Calculated chemistry of [ 71616-83-6 ]

Physicochemical Properties

Num. heavy atoms : 15
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.33
Num. rotatable bonds : 5
Num. H-bond acceptors : 3.0
Num. H-bond donors : 0.0
Molar Refractivity : 57.53
TPSA : 43.37 Ų

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : Yes
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -5.75 cm/s

Lipophilicity

Log Po/w (iLOGP) : 2.47
Log Po/w (XLOGP3) : 2.54
Log Po/w (WLOGP) : 2.46
Log Po/w (MLOGP) : 2.16
Log Po/w (SILICOS-IT) : 2.81
Consensus Log Po/w : 2.49

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -2.68
Solubility : 0.426 mg/ml ; 0.00207 mol/l
Class : Soluble
Log S (Ali) : -3.1
Solubility : 0.165 mg/ml ; 0.000798 mol/l
Class : Soluble
Log S (SILICOS-IT) : -3.62
Solubility : 0.0489 mg/ml ; 0.000237 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.41

Safety of [ 71616-83-6 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P264-P270-P301+P312-P330 UN#:N/A
Hazard Statements:H302 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 71616-83-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 71616-83-6 ]

[ 71616-83-6 ] Synthesis Path-Downstream   1~45

  • 1
  • [ 2234-82-4 ]
  • [ 203442-83-5 ]
  • [ 71616-83-6 ]
YieldReaction ConditionsOperation in experiment
23.7% To a solution of N-methoxy-N-methyl-terephthalamic acid methyl ester (4.56 g, 20.4 mmol) in THF (100 mL) is added PrMgCl (2.0M, 30.6 mmol) at 0 C, the reaction is warmed to room temperature, stirred overnight, quenched by NH4Cl aqueous solution, extracted with ethyl acetate. The combined organic layers are washed with brine, dried over sodium sulfate, concentrate. Column chromatography on silica gel gives the title compound (1 g, 23.7 %).
  • 2
  • [ 71616-83-6 ]
  • [ 872254-79-0 ]
YieldReaction ConditionsOperation in experiment
To a solution of <strong>[71616-83-6]4-butyryl-benzoic acid methyl ester</strong> (400 mg, 1.94 mmol) in ethanol (5 mL) and THF (4 mL) is added sodium borohydride (110 mg, 2.9 mmol), the mixture is stirred at room temperature for 2 h. The reaction mixture is quenched by acetic acid (0.5 mL) and water (10 mL), extracted with ethyl acetate. Combined organic layers are washed with brine and dried over sodium sulfate. Concentration and column chromatography on silica gel gives the title compound (370 mg).
  • 3
  • [ 67-56-1 ]
  • [ 858114-91-7 ]
  • [ 201230-82-2 ]
  • [ 71616-83-6 ]
YieldReaction ConditionsOperation in experiment
49% With hydrogenchloride; triethylamine;palladium diacetate; 1,3-bis-(diphenylphosphino)propane; In dimethyl sulfoxide; at 80℃; for 8h; Reference Example 46 methyl 4-butyrylbenzoate A mixture of 4-butyrylphenyl trifluoromethanesulfonate (27.1 g, 91.7 mmol), palladium (II) acetate (1.24 g, 5.50 mmol), 1,3-bis(diphenylphosphino)propane (2.45 g, 6.05 mmol), triethylamine (23.2 g, 229 mmol), methanol (200 mL) and dimethyl sulfoxide (100 mL) was heated under reflux under a CO atmosphere at 80C for 8 hr. After cooling the reaction mixture, 0.5N hydrochloric acid was added, and the mixture was extracted with ethyl acetate. The extract was washed with saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate:hexane = 3:97-30:70) and recrystallized from ethyl acetate-hexane to give the title compound (9.24 g, yield 49%) as colorless crystals. MS: m/z 207 (M+H).
49% With triethylamine;palladium diacetate; 1,3-bis-(diphenylphosphino)propane; In dimethyl sulfoxide; at 80℃; for 8h; A mixture of 4-butyrylphenyl trifluoromethanesulfonate (27.14 g, 91.7 mmol), palladium acetate (1.24 g, 5.50 mmol), 1,3-bis(diphenylphosphino)propane (2.45 g, 6.05 mmol), triethylamine (23.2 g, 229 mmol), methanol (200 mL) and dimethyl sulfoxide (100 mL) was heated under reflux under a carbon monoxide atmosphere at 80C for 8 hr. After cooling the reaction mixture, 0.5 N hydrochloric acid was added, and the mixture was extracted with ethyl acetate. The extract was washed with saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate/hexane=3/97-30/70) and recrystallized from ethyl acetate-hexane to give the title compound (9.24 g, yield 49%) as colorless crystals. MS: m/z 207 (MH+).
  • 4
  • [ 71616-83-6 ]
  • [ 78502-88-2 ]
  • C22H23NO2S [ No CAS ]
YieldReaction ConditionsOperation in experiment
Reference Example 47 (4-{1-[(4-phenyl-1,3-thiazol-2-yl)methyl]butyl}phenyl)methanol To a suspension of triphenyl[(4-phenyl-1,3-thiazol-2-yl)methyl]phosphonium bromide (1.00 g, 1.94 mmol) synthesised according to the method described in Liebigs Annalen der Chemie, vol. 4, pages 623-632, 1981 in benzene (20 mL) was added potassium-t-butoxide (239 mg, 2.13 mmol), and the mixture was stirred under an argon atmosphere at room temperature for 3 hr. To a reaction solution was added dropwise a solution of <strong>[71616-83-6]methyl 4-butyrylbenzoate</strong> (319 mg, 1.55 mmol) in benzene (20 mL), and the mixture was stirred at room temperature for 3 hr and then heated under reflux for 16 hr. The reaction mixture was cooled to room temperature, poured into water and extracted with ethyl acetate. The extract was washed with saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate:hexane = 5:95-20:80) to give a yellow oil. Tetrahydrofuran (20 mL), methanol (10 mL) and 10% palladium-carbon (200 mg) were added to the oil, and the mixture was stirred under a hydrogen atmosphere at room temperature for 2 days. The catalyst was filtered off, and the obtained filtrate was concentrated to give a colorless oil. To a solution of the oil in tetrahydrofuran (10 mL) was added dropwise 1.0M diisobutyl aluminum hydride toluene solution (10 mL, 10 mmol) under ice-cooling. The reaction mixture was stirred at room temperature for 2 hr, sodium sulfate 10 hydrate was added, and the mixture was further stirred at room temperature for 1 hr. The insoluble materials were filtered off and the filtrate was concentrated. The residue was purified by silica gel column chromatography (ethyl acetate:hexane = 10:90-60:40) to give the title compound (250 mg, yield 48%) as a colorless oil. MS: m/z 338 (M+H).
  • 5
  • [ 71616-83-6 ]
  • [ 78502-88-2 ]
  • C22H21NO2S [ No CAS ]
YieldReaction ConditionsOperation in experiment
To a suspension of triphenyl[(4-phenyl-1,3-thiazol-2-yl)methyl]phosphonium bromide (1.00 g, 1.94 mmol) synthesised according to the method described in and benzene (20 mL) was added potassium tert-butoxide (239 mg, 2.13 mmol), and the mixture was stirred under an argon atmosphere at room temperature for 3 hr. A solution of <strong>[71616-83-6]methyl 4-butyrylbenzoate</strong> (319 mg, 1.55 mmol) in benzene (20 mL) was added dropwise to the reaction solution, and the mixture was stirred at room temperature for 3 hr, and further heated under reflux for 16 hr. The reaction mixture was allowed to cool to room temperature, poured into water, and the mixture was extracted with ethyl acetate. The extract was washed with saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate:hexane=5:95-20:80) to give a yellow oil. A mixture of the obtained oil, tetrahydrofuran (20 mL), methanol (10 mL) and 10% palladium-carbon (50% water-containing product, 200 mg) was stirred under a hydrogen atmosphere at room temperature for 2 days. The catalyst was filtered off, and the obtained filtrate was concentrated to give a colorless oil. To a solution of the obtained oil in tetrahydrofuran (10 mL) was added dropwise 1.0 M diisobutylaluminum hydride toluene solution (10 mL, 10 mmol) under ice-cooling. The reaction mixture was stirred at room temperature for 2 hr, sodium sulfate decahydrate was added and the mixture was further stirred at room temperature for 1 hr. The insoluble material was filtered off, the filtrate was concentrated, and the residue was purified by silica gel column chromatography (ethyl acetate/hexane=10/90-60/40) to give the title compound (250 mg, yield 48%) as a colorless oil. MS: m/z 338 (MH+).
  • 6
  • S-2-(1-(methoxyimino)ethyl)phenyl butanethioate [ No CAS ]
  • [ 99768-12-4 ]
  • [ 71616-83-6 ]
  • 7
  • [ 1571-08-0 ]
  • [ 71616-83-6 ]
  • 8
  • [ 71616-83-6 ]
  • [ 71616-82-5 ]
YieldReaction ConditionsOperation in experiment
Intermediate (21) (256.1 mg, 1.242 mmol) was dissolved in tetrahydrofuran (3 mL) and methanol (3.0 mL). 1N NaOH (3.73 mL) was added and the reaction was heated to 50 C. for 3 hours. The reaction was then cooled to room temperature and concentrated. The crude residue was taken up in water and acidified to pH=5 with 1N HCl. A white precipitate formed. The solids were filtered off and dried under vacuum to give 4-butyrylbenzoic acid (155.4 mg, 65%) as a white solid. 1H NMR (400 MHz, CDCl3, delta): 8.16-8.21 (m, 2H), 8.01-8.05 (m, 2H), 2.98 (t, J=7.2 Hz, 2H), 1.78 (m, 2H), 1.01 (t, J=7.41 Hz, 3H).
  • 9
  • [ 872254-79-0 ]
  • [ 71616-83-6 ]
YieldReaction ConditionsOperation in experiment
95.2% With pyridinium chlorochromate; In dichloromethane; at 0 - 20℃; for 18h; A mixture of methyl 4- (1-hydroxybutyl) benzoate1b (6.58 g, 31.6 mmol) was dissolved in 100 mL of dichloromethane,At 0 & lt; 0 & gt;Adding pyridine chlorochromate(8.17 g, 37.9 mmol),Room temperature reaction for 18 hours.Diluted with 200 mL of dichloromethane,The mixture was stirred with anhydrous magnesium sulfate for 10 minutes,filter,Concentrated under reduced pressure,The resulting residue was purified by silica gel column chromatography(Eluent: petroleum ether: ethyl acetate system)To give methyl 4-butyrylbenzoate 1c (6.20 g, white solid), yield: 95.2%
With sulfur trioxide pyridine complex; triethylamine; In dichloromethane; dimethyl sulfoxide; at 10 - 20℃; for 16.5h; To a solution of Intermediate 64 (129.5 g, 565.9 mmol) in dichloromethane (129.5 mL) was added triethylamine (394.4 mL, 2.83 mol). The solution was cooled to 10 C, then a solution of sulfur trioxide pyridine complex (202.2 g, 1 .24 mol) in dimethyl sulfoxide (777.0 mL) was added slowly over 30 minutes, keeping the internal temperature below 15 C. The reaction was warmed to 25 C. After 16 hours, the mixture was diluted slowly with hydrochloric acid (1.22 M in water, 2780 mL). The reaction was stirred for 15 minutes, then the layers were separated. The organic layer was washed with water (1000 mL), then treated with Darco KB-B (13 g), magnesiumsulfate (13 g), and celite and slurried for 30 minutes. The slurry was filtered, and the solids were washed with methyl tert-butyl ether (250 mL). The filtrate was concentrated at atmospheric pressure (internal temperature 55-58 C) to a volume of approximately 500 mL. This solution was cooled at 2 C/minute to 15 C. Heptane (250 mL) was added, and the slurry was cooled to 10 C and stirred for 1 hour. The slurry was filtered, and the solids were washed with 1 :2 methyl tert-butyl ether: heptane (260 mL, cooled to 5 C) then heptane (250 mL). The resulting off-white solid was dried under vacuum to provide Intermediate X202. 1 H NMR (400 MHz, CDCI3, delta): 8.08 - 8.13 (m, 2 H), 7.97 - 8.01 (m, 2 H), 3.94 (s, 3 H), 2.96 (t, J = 7.3 Hz, 2 H), 1.77 (m, 2 H), 1.00 (t, J = 7.4 Hz, 3 H).
  • 11
  • [ 71616-83-6 ]
  • [ 1383803-08-4 ]
  • 12
  • [ 71616-83-6 ]
  • [ 1393123-89-1 ]
  • 13
  • [ 71616-83-6 ]
  • [ 1393126-67-4 ]
  • 14
  • [ 71616-83-6 ]
  • [ 1393124-90-7 ]
  • [ 1393124-89-4 ]
  • 15
  • [ 71616-83-6 ]
  • [ 1393125-29-5 ]
  • [ 1393126-53-8 ]
YieldReaction ConditionsOperation in experiment
With decaborane; In methanol; at 20℃;Inert atmosphere; Step A: (+/-)-methyl-4-(1-(3-methyl-4-(4-(trifluoromethyl)-1H-imidazol-1-yl)phenylamino)butyl)benzoate To a solution of Intermediate (21) (248 mg, 1.2 mmol) and Intermediate (4) (290 mg, 1.2 mmol) in methanol (12 mL) was added decaborane (44.1 mg, 0.36 mmol) at room temperature under nitrogen. The resulting solution was stirred at room temperature overnight. The reaction was concentrated and purification by column chromatography (0-35% ethyl acetate in heptane), gave (+/-)-methyl-4-(1-(3-methyl-4-(4-(trifluoromethyl)-1H-imidazol-1-yl)phenylamino)butyl)benzoate as a foam. 1H NMR (500 MHz, CDCl3, delta): 8.02 (d, J=8.29 Hz, 2H), 7.48 (s, 1H), 7.42 (d, J=8.29 Hz, 2H), 7.25 (s, 1H), 6.90 (d, J=8.54 Hz, 1H), 6.41 (m, 1H), 6.34 (m, 1H), 4.40 (m, 2H), 3.91 (s, 3H), 1.98 (s, 3H), 1.72-1.87 (m, 2H), 1.34-1.52 (m, 2H), 0.96 (t, J=7.32 Hz 3H). MS (M+1): 432.4.
  • 16
  • [ 619-44-3 ]
  • [ 71616-83-6 ]
  • 17
  • [ 71616-83-6 ]
  • C13H18O5S [ No CAS ]
  • 18
  • [ 71616-83-6 ]
  • C12H15N3O2 [ No CAS ]
  • 19
  • [ 71616-83-6 ]
  • [ 1421349-08-7 ]
YieldReaction ConditionsOperation in experiment
With borane N,N-diethylaniline complex; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; In tetrahydrofuran; toluene; at 20℃; for 0.166667h; Intermediate 66: (S)-methyl 4-(1-hydroxybutyl)benzoate To a solution of borane-diethylaniline complex (49.79 mL, 280.0 mmol) and (R)- (+)-2-methyl-CBS-oxaborolidine solution (1 M in toluene, 18.67 mL, 18.67 mmol) in tetrahydrofuran (154 mL) at 20 C was added a solution of Intermediate 65 (77.00 g, 373.4 mmol) in tetrahydrofuran (385 mL) over 2 hours. After stirring for 10 minutes, the reaction was quenched by slow addition of methanol (34.75 mL, 858.7 mmol) over 30 minutes while maintaining the temperature below 20 C. Hydrochloric acid (1 N in water, 373.4 mL, 373.4 mmol) was then added over 10 minutes while maintaining the temperature below 20 C. Methyl tert-butyl ether (385 mL) was added and mixture was stirred for 30 minutes. The layers were separated. Hydrochloric acid (1 N in water, 373.4 mL)was added to the organic layer, and the mixture was stirred for 10 minutes. The layers were separated, and the organic layer was diluted with water (77.0 mL). The mixture was stirred for 5 minutes, then the layers were separated. The combined aqueous layers were back-extracted with methyl tert-butyl ether (2 x 150 mL). The combined organic layers were distilled at atmospheric pressure (temperature less than 80 C) until 250 mL of solution remained. The solution was then diluted with heptane (847 mL) and distilled at atmospheric pressure (100-1 10 C) until 650 mL of solvent had been distilled. Again, heptane (462 mL) was added, and the solution was distilled at atmospheric pressure (100-1 10 C) until the internal temperature reached 100 C. Heptane was added to a total volume of 700 mL. The solution was then cooled to -15C with vigorous stirring. The slurry was warmed to 15 C and stirred overnight. The mixture was then cooled to -15 C and stirred for 3.5 hours. The resulting slurry was filtered, and the solid was washed with heptane (50 mL, cooled to 0 C). The resulting solid was dried under vacuum to provide Intermediate 66. 1 H NMR (400 MHz, CDCI3, delta): 7.97 - 8.02 (m, 2 H), 7.40 (d, J = 8.4 Hz, 2 H), 4.74 (dd, J = 7.8, 5.7 Hz, 1 H), 3.90 (s, 3 H), 1.61 - 1.82 (m, 2 H), 1.23 - 1.49 (m, 2 H), 0.92 (t, J = 7.32 Hz, 3 H).
  • 20
  • [ 71616-83-6 ]
  • [ 1213123-33-1 ]
  • 21
  • [ 106-37-6 ]
  • [ 71616-83-6 ]
  • 22
  • [ 67-56-1 ]
  • [ 201230-82-2 ]
  • [ 4981-64-0 ]
  • [ 71616-83-6 ]
YieldReaction ConditionsOperation in experiment
85% With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; triethylamine; at 90℃; under 11400.8 Torr; for 12h; [00109] Into a 2000-mL pressure tank reactor (CO, 15 atm), was placed a solution of 1-(4-bromophenyl)butan-1-one (58 g, 255.51 mmol, 1.00 equiv) in methanol (1200 mL), triethylamine (51 g, 504.95 mmol, 2.00 equiv), 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex (9.42 mg, 0.01 mmol, 0.05 equiv). The resulting solution was stirred for 12 h at 90C. The solids were filtered out. The resulting mixture was concentrated under reduced pressure. The residue was applied onto a silica gel column eluting with ethyl acetate/petroleum ether (1:20-1:10). This resulted in 45 g (85%) of methyl 4-butyrylbenzoate as a white solid.
  • 23
  • [ 71616-83-6 ]
  • methyl 4-(2-bromobutanoyl)benzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
95% With pyridinium hydrobromide perbromide; In tetrahydrofuran; at 75℃; for 2h; [00110] Into a 250-mL round-bottom flask, was placed a solution of <strong>[71616-83-6]methyl 4-butyrylbenzoate</strong> (8 g, 36.89 mmol, 1.00 equiv, 95%) in tetrahydrofuran (150 mL), pyridinium tribromide (19.2 g, 60.00 mmol, 1.50 equiv). The resulting solution was stirred for 2 h at 75C in an oil bath. The reaction was then quenched by the addition of 200 mL of water. The pH value of the solution was adjusted to 8-9 with saturated sodium bicarbonate. The resulting solution was extracted with 3x200 mL of ethyl acetate and the organic layers combined. The resulting mixture was washed with 3x200 mL of water and 3x200 mL of brine. The mixture was dried over anhydrous magnesium sulfate. This resulted in 10 g (95%) of methyl 4-(2-bromobutanoyl)benzoate as a red brown liquid.
  • 24
  • [ 71616-83-6 ]
  • methyl 4-(5-ethyl-2-(5-methylpyrazin-2-yl)thiazol-4-yl)benzoate [ No CAS ]
  • 25
  • [ 71616-83-6 ]
  • methyl 4-(5-ethyl-2-(5-methylisoxazol-3-yl)thiazol-4-yl)benzoate [ No CAS ]
  • 26
  • [ 71616-83-6 ]
  • N-(2,4-dimethylpyridin-5-yl)-4-[5-ethyl-2-(5-methylpyrazin-2-yl)thiazol-4-yl]benzamide [ No CAS ]
  • 27
  • [ 71616-83-6 ]
  • 4-[5-ethyl-2-(5-methylisoxazol-3-yl)thiazol-4-yl]-N-(4-methylpyrimidin-5-yl)benzoate [ No CAS ]
  • 28
  • [ 71616-83-6 ]
  • (R)-4-(1-hydroxybutyl)benzoic acid methyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
97.0% With borane Nu,Nu-diethylaniline complex; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole; In tetrahydrofuran; at 20℃; for 0.5h; Borane borane-N, N-diethylaniline(5.53 mL, 30.0 mmol) was dissolved in 100 mL of tetrahydrofuran,Join(S) -2-methyl-CBS-oxazaborolidine(1.5 mL, 1.50 mmol),Then a solution of <strong>[71616-83-6]methyl 4-butyrylbenzoate</strong> 1c (6.20 g, 30.0 mmol) in tetrahydrofuran (50 mL)Solution,The reaction was carried out for 0.5 hour at room temperature.The reaction was quenched by the dropwise addition of 10 mL of methanol,Then 1M hydrochloric acid (130 mL) and petroleum ether (300 mL) were added,The organic phase was washed with 1 M hydrochloric acid (120 mL) and saturated sodium chloride solution (100 mL)Dried over anhydrous sodium sulfate, filtered, concentrated under reduced pressure,(R) -4- (1-hydroxybutyl) benzoate 1d (6.07 g, colorless liquid) was obtained,Yield: 97.0%
  • 29
  • [ 71616-83-6 ]
  • [ 1393126-80-1 ]
  • 30
  • [ 71616-83-6 ]
  • (3R)-1-(4-((1R)-1-hydroxybutyl)benzoyl)piperidine-3-carboxylic acid ethyl ester [ No CAS ]
  • 31
  • [ 71616-83-6 ]
  • (R)-1-(4-((S)-1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzoyl)piperidine-3-carboxylate [ No CAS ]
  • 32
  • [ 71616-83-6 ]
  • C21H31NO4 [ No CAS ]
  • 33
  • [ 71616-83-6 ]
  • 2-(R)-1-(4-((S)-1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzoyl)piperidine-3-carboxylic acid ethyl ester [ No CAS ]
  • 34
  • [ 71616-83-6 ]
  • 2-(R)-1-(4-((S)-1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzoyl)piperidine-3-carboxylic acid [ No CAS ]
  • 35
  • [ 71616-83-6 ]
  • (R)-ethyl-5,5-difluoro-1-(4-((R)-1-hydroxyethyl)benzoyl)carboxylic acid methyl ester [ No CAS ]
  • 36
  • [ 71616-83-6 ]
  • 1-(4-((S)-1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzoyl)-5,5-difluoropiperidine-3-carboxylic acid methyl ester [ No CAS ]
  • 37
  • [ 71616-83-6 ]
  • 1-(4-((S)-1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzoyl)-5,5-difluoropiperidine-3-carboxylic acid [ No CAS ]
  • 38
  • [ 71616-83-6 ]
  • (R)-1-(4-((S)-1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzoyl)piperidine-3-carboxylic acid [ No CAS ]
  • 39
  • [ 1679-64-7 ]
  • [ 71616-83-6 ]
  • 40
  • [ 1009-11-6 ]
  • [ 71616-83-6 ]
  • 41
  • [ 557-93-7 ]
  • [ 1571-08-0 ]
  • [ 71616-83-6 ]
  • 42
  • [ 71616-83-6 ]
  • methyl (E)-4-(1-(((perfluorobenzoyl)oxy)imino)butyl)benzoate [ No CAS ]
  • 45
  • [ 72824-04-5 ]
  • [ 1571-08-0 ]
  • [ 71616-83-6 ]
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[ 68634-02-6 ]

Methyl 1-oxo-2,3-dihydro-1H-indene-5-carboxylate

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Chemical Structure| 55934-10-6

[ 55934-10-6 ]

Methyl 1-oxo-2,3-dihydro-1H-indene-4-carboxylate

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Chemical Structure| 1077-79-8

[ 1077-79-8 ]

Methyl 2-acetylbenzoate

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Chemical Structure| 3609-53-8

[ 3609-53-8 ]

Methyl 4-acetylbenzoate

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