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Chemical Structure| 701-26-8 Chemical Structure| 701-26-8

Structure of 701-26-8

Chemical Structure| 701-26-8

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Product Details of [ 701-26-8 ]

CAS No. :701-26-8
Formula : C10H13F
M.W : 152.21
SMILES Code : FC1=CC(C(C)(C)C)=CC=C1

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Application In Synthesis of [ 701-26-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 701-26-8 ]

[ 701-26-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5369-19-7 ]
  • [ 701-26-8 ]
YieldReaction ConditionsOperation in experiment
71% With tetrafluoroboric acid; at 25℃; for 0.5h; To 40percent fluoroboric acid (40 mL) was added <strong>[5369-19-7]3-tert-butylaniline</strong> (5.5 g, 37 mmol) portion- wise. The mixture was stirred at 25 °C for 0.5 hour and then cooled to 0 °C. Sodium nitrite (4.1 g, 59 mmol) in water (10 mL) was added, and the solution was stirred at 0 °C for 0.5 hour and at 25°C for 20 mins, resulting in formation of a sold. The solid was collected by filtration, washed with 40percent fluoroboric acid (10 mL), ethanol (5 mL) and n-hexane (10 mL), dried, dissolved in tetrahydrofuran (60 mL) and stirred at 40 °C for 12 hours. On completion, the mixture was concentrated, and the residue was purified by silica gel chromatography [petroleum ether: ethyl acetate = 1:0] to afford compound A- 17 (4.0 g, 71percent yield) as a yellow oil
 

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