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Chemical Structure| 693792-98-2 Chemical Structure| 693792-98-2

Structure of 693792-98-2

Chemical Structure| 693792-98-2

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Product Details of [ 693792-98-2 ]

CAS No. :693792-98-2
Formula : C18H20BrNO2
M.W : 362.26
SMILES Code : O=C(OC(C)(C)C)N(CC1=CC=CC=C1)C2=CC=C(Br)C=C2
MDL No. :MFCD17011978

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Application In Synthesis of [ 693792-98-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 693792-98-2 ]

[ 693792-98-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 100-39-0 ]
  • [ 131818-17-2 ]
  • [ 693792-98-2 ]
YieldReaction ConditionsOperation in experiment
100% With sodium hydride; In tetrahydrofuran; at 0 - 60℃; for 5h; To a solution of tert-butyl (4-bromophenyl) carbamate (0.50 g, 1.84 mmol) and benzyl bromide (0.262 mL, 2.20 mmol) in tetrahydrofuran (20 mL) was added sodium hydride (60% in oil, 0. 11 g, 2.76 mmol) at 0C, and the mixture was stirred at room temperature for 1 hour and THEN-AT 60C for 4 hours. After cooled to room temperature, the reaction mixture was quenched with saturated ammonium chloride solution, and extracted with ethyl acetate. The separated organic phase was washed with brine, dried over sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography on silica-gel (hexane: ethyl acetate,. 9: 1) to give ter-butyl benzyl (4-bromophenyl) carbamate (0.68 g, 100%) as colorless oil.
 

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