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Chemical Structure| 6760-22-1 Chemical Structure| 6760-22-1

Structure of 6760-22-1

Chemical Structure| 6760-22-1

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Product Details of [ 6760-22-1 ]

CAS No. :6760-22-1
Formula : C11H9NO
M.W : 171.20
SMILES Code : O=CC1=CC(C)=NC2=CC=CC=C12
MDL No. :MFCD08052651

Safety of [ 6760-22-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 6760-22-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6760-22-1 ]

[ 6760-22-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50488-44-3 ]
  • [ 6760-22-1 ]
YieldReaction ConditionsOperation in experiment
34% With hydrogenchloride; n-butyllithium; In tetrahydrofuran; N-methyl-acetamide; ethanol; B. 2-Methyl-4-quinolinecarbaldehyde To a solution of <strong>[50488-44-3]4-bromo-2-methylquinoline</strong> (4.71g, 21.2 mmol) in dry tetrahydrofuran (50 ml) under nitrogen at -78 was added 1.5M n-butyllithium in hexanes (13.5 ml). After 2 minutes, dry dimethylformamide (2.0 ml, 25 mmol) was added. After an additional 3 minutes at -78, ethanol (5 ml) was added, followed by 1N hydrochloric acid. After 5 minutes, at 25, the solution was neutralised with sodium hydroxide and extracted with methylene chloride (4 x 50ml). The methylene chloride solution was dried (MgSO4) and passed through a silica gel pad to give the title compound as yellow crystals (1.24g, 34%);, mp 72-75. Anal . Calcd for C11H9NO1/10H2O: C, 76.37; H, 5.36; N, 8.10. Found: C, 76.13; H, 5.44; N, 7.96.
 

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