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Chemical Structure| 6592-18-3 Chemical Structure| 6592-18-3

Structure of 6592-18-3

Chemical Structure| 6592-18-3

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Product Details of [ 6592-18-3 ]

CAS No. :6592-18-3
Formula : C16H14N2O2
M.W : 266.29
SMILES Code : COC1=CC(OC)=C(C2=NC3=CC=CC=C3N=C2)C=C1

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Application In Synthesis of [ 6592-18-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6592-18-3 ]

[ 6592-18-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1448-87-9 ]
  • [ 133730-34-4 ]
  • [ 6592-18-3 ]
YieldReaction ConditionsOperation in experiment
77% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; water; at 80℃; for 24h; General procedure: 2-Phenylquinoxaline (pqx) was prepared from a reaction of 2-chloroquinoxaline and phenylboronic acid. 2-Chloroquinoxaline(3.00 g, 18.2 mmol), phenylboronic acid (2.44 g,20.0 mmol) and tetrakis(triphenylphosphine)palladium(0)(0.98 g, 0.85 mmol) were added to 50 mL of THF. After adding 5 mL of aqueous 4 M K2CO3, the reaction mixture was heated to 80 C for 24 h. The cooled crude mixture was poured into water, extracted with CH2Cl2 (50 mL × 3 times)and dried over anhydrous magnesium sulfate. Finally, silica column purification (n-hexane:EtOAc = 5:1) gave 3.15 g of a white solid in quantitative yield (84%).
 

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