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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 611226-35-8 Chemical Structure| 611226-35-8

Structure of 611226-35-8

Chemical Structure| 611226-35-8

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Product Details of [ 611226-35-8 ]

CAS No. :611226-35-8
Formula : C11H13NS
M.W : 191.29
SMILES Code : S=C=NC1=CC=CC(C(C)(C)C)=C1
MDL No. :MFCD09878144

Safety of [ 611226-35-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H312-H315-H319-H332-H335-H334
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 611226-35-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 611226-35-8 ]

[ 611226-35-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5369-19-7 ]
  • [ 16420-13-6 ]
  • [ 611226-35-8 ]
YieldReaction ConditionsOperation in experiment
In toluene; for 5h;Reflux; General procedure: Taking the synthesis of 18 3-(trifluoromethyl)phenyl 1-isothiocyanate as an example, 19 3-(trifluoromethyl)aniline (2.38g, 14.77mmol, 1 eqv) and 20 dimethylamino thiocarbonyl chloride (1.92g, 15.50mmol, 1.05 eqv) were added in dry 21 toluene (20mL) at room temperature, and then the reaction mixture was refluxed for 5h. After the reaction mixture was cooled down to room temperature, the solid dimethylamine hydrochloride was filtered off, and the collected toluene fraction was removed under reduced pressure. Colorless oil (2.55g, 85%) was obtained and used in the next step without additional purification. The other aromatic isothiocyanates were synthesized in the same way.
 

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