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Chemical Structure| 603310-64-1 Chemical Structure| 603310-64-1

Structure of 603310-64-1

Chemical Structure| 603310-64-1

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Product Details of [ 603310-64-1 ]

CAS No. :603310-64-1
Formula : C13H14N2O2
M.W : 230.26
SMILES Code : O=C(OCC)CC1=CN=C2C=CC(C=C)=CN21

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Application In Synthesis of [ 603310-64-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 603310-64-1 ]

[ 603310-64-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 603311-76-8 ]
  • [ 7486-35-3 ]
  • [ 603310-64-1 ]
YieldReaction ConditionsOperation in experiment
55% tetrakis(triphenylphosphine) palladium(0); at 110℃; for 16h; Preparation 178; 2-(6-ethylimidazo [1, 2-a] pyridin-3-yl) acetamide; Ethyl 2- (6-vinylimidazopyridinf 1, 2-alpyridin-3-yl) acetate; Bubble nitrogen into a mixture of ethyl 2- (6-bromoimidazo [1, 2-a] pyridin-3-yl)- acetate (2.0 g, 7.0 mmol), vinyltributyltin (3.3 g, 11 mmol) and tetrakis (triphenyl- phosphine) Pd (0) (0.25 mg) in a resealable tube in toluene for 3 minutes. Heat and stir at 110°C for 16 hours. Cool and concentrate under reduced pressure. Subject the residue to silica gel chromatography, eluting with hexane/ethyl acetate; 1: 1 to 0: 1 provide the desired compound (0.90 g, 55percent). MS (ES): m/z = 231 (M++H).
 

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