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Chemical Structure| 5959-39-7 Chemical Structure| 5959-39-7

Structure of 5959-39-7

Chemical Structure| 5959-39-7

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Product Details of [ 5959-39-7 ]

CAS No. :5959-39-7
Formula : C6H6Cl3NO
M.W : 214.48
SMILES Code : OC1=C(Cl)C=C(Cl)C=C1N.[H]Cl

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Application In Synthesis of [ 5959-39-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5959-39-7 ]

[ 5959-39-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 609-89-2 ]
  • [ 5959-39-7 ]
YieldReaction ConditionsOperation in experiment
With iron; ammonium chloride; In tetrahydrofuran; ethanol; water; at 90℃; step 1 Production of 2-amino-4,6-dichlorophenol hydrochloride 2,4-Dichloro-6-nitrophenol (12 g) was dissolved in tetrahydrofuran (40 mL) and ethanol (70 mL) and water (60 mL), ammonium chloride (15.4 g) and iron (16.1 g) were added, and the mixture was stirred with heating at 90 C. The insoluble material was removed by celite filtration, and the filtrate was concentrated and extracted with ethyl acetate. Anhydrous sodium sulfate, silica gel and activated carbon were added to the obtained ethyl acetate layer and the mixture was filtered through celite. The filtrate was concentrated, and the obtained residue was dissolved in ethyl acetate, 4N hydrogen chloride (ethyl acetate solution) was added, and the precipitated solid was collected by filtration to give the title compound (9.30 g) as a gray solid.
 

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