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Chemical Structure| 58966-35-1 Chemical Structure| 58966-35-1

Structure of 58966-35-1

Chemical Structure| 58966-35-1

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Product Details of [ 58966-35-1 ]

CAS No. :58966-35-1
Formula : C9H9ClO
M.W : 168.62
SMILES Code : CC(C1=CC(Cl)=CC=C1C)=O
MDL No. :MFCD11113486

Safety of [ 58966-35-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 58966-35-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 58966-35-1 ]

[ 58966-35-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 27139-97-5 ]
  • [ 75-36-5 ]
  • [ 58966-35-1 ]
YieldReaction ConditionsOperation in experiment
To a suspension of magniesium (0.12 g) in THF (15 ml_) <strong>[27139-97-5]2-bromo-4-chlorotoluene</strong> (0.125 g, commercially available) was added and the mixture stirred for a few minutes. Then a solution of <strong>[27139-97-5]2-bromo-4-chlorotoluene</strong> (0.9 g) in THF (85 ml_) was added dropwise and the mixture stirred for 3h. The mixture was added dropwise to a solution of acetyl chloride(0.353 g) in THF (10 ml_) at 0 0C. The mixture was stirred at RT for 5h. Chilly water was added to the reaction mixture and the pH adjusted at pH 6 with HCI 10percent and the product extracted with EA. The organic phase was dried and the solvent evaporated under vacuum to give the title compound (0.676 g) that was used in next step without further purification.MS (m/z): 169 [MH]+
 

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