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Chemical Structure| 52334-79-9 Chemical Structure| 52334-79-9

Structure of 52334-79-9

Chemical Structure| 52334-79-9

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Product Details of [ 52334-79-9 ]

CAS No. :52334-79-9
Formula : C6H8N2O
M.W : 124.14
SMILES Code : OC1=NC(C)=CC=C1N
MDL No. :MFCD07774135

Safety of [ 52334-79-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 52334-79-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 52334-79-9 ]

[ 52334-79-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 39745-39-6 ]
  • [ 52334-79-9 ]
YieldReaction ConditionsOperation in experiment
With hydrogen;palladium 10% on activated carbon; In methanol; dichloromethane; at 20℃; for 2h; a) Synthesis of 3-amino-6-methyl-pyridin-2-ol <strong>[39745-39-6]6-hydroxy-5-nitro-2-picoline</strong> (500 mg, 3.247 mmol) was dissolved in methanol:dichloromethane (5:1, 60 ml) and 10% palladium on active carbon was added thereto slowly, and then stirred for 2 hours with adding hydrogen gas at room temperature. The reaction mixture was filtered by using celite and evaporated under reduced pressure to quantitatively obtain white solid (400 mg). 1H-NMR (CDCl3, 300 MHz); delta=11.67 (br s, 1H), 6.57 (d, J=7.2 Hz, 1H), 5.88 (d, J=7.2 Hz, 1H), 3.20 (br s, 2H), 2.25 (s, 3H). MS (ESI); 125.1 (M++1).
 

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