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Chemical Structure| 51761-07-0 Chemical Structure| 51761-07-0

Structure of 9H-Carbazole-3-carbaldehyde
CAS No.: 51761-07-0

Chemical Structure| 51761-07-0

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Product Details of [ 51761-07-0 ]

CAS No. :51761-07-0
Formula : C13H9NO
M.W : 195.22
SMILES Code : O=CC1=CC2=C(C=C1)NC3=C2C=CC=C3
MDL No. :MFCD09743119
InChI Key :WRBOHOGDAJPJOQ-UHFFFAOYSA-N
Pubchem ID :504067

Safety of [ 51761-07-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H332
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Application In Synthesis of [ 51761-07-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 51761-07-0 ]

[ 51761-07-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 54117-37-2 ]
  • [ 51761-07-0 ]
YieldReaction ConditionsOperation in experiment
40% Step 3. 9H-Carbazole-3-carbaldehyde; A 250-mL round-bottomed flask was charged with a solution of AlCl3 (9.26 g, 69.45 mmol, 20.00 equiv, 99%) in 1,2-dichloroethane (150 mL). To this was added <strong>[54117-37-2]9-benzyl-9H-carbazole-3-carbaldehyde</strong> (1 g, 3.47 mmol, 1.00 equiv, 99%) in several batches at room temperature over 5 minutes. The resulting mixture was stirred for 2 hours at room temperature. The reaction was then quenched by the addition of H2O/ice (100 mL). The solids were filtered out. The resulting solution was extracted with DCM (3×100 mL) and the combined organic layers were concentrated on a rotary evaporator to give a residue that was purified by silica gel column chromatography eluted with PE:EtOAc (10:1) to afford 9H-carbazole-3-carbaldehyde as green solid (270 mg, 40%). LCMS: [M+H]+: 196
 

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