Alternatived Products of [ 5170-68-3 ]
Product Details of [ 5170-68-3 ]
CAS No. : | 5170-68-3 |
MDL No. : | MFCD02681902 |
Formula : |
C7H4N2OS
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | ANVJARPTPIVPRC-UHFFFAOYSA-N |
M.W : |
164.18
|
Pubchem ID : | 2776283 |
Synonyms : |
|
Application In Synthesis of [ 5170-68-3 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 5170-68-3 ]
- 1
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[ 1457-92-7 ]
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[ 5170-68-3 ]
Reference:
[1]Heterocycles,1997,vol. 45,p. 955 - 962
[2]Heterocycles,1997,vol. 45,p. 955 - 962
[3]European Journal of Medicinal Chemistry,1993,vol. 28,p. 141 - 148
[4]European Journal of Medicinal Chemistry,1993,vol. 28,p. 141 - 148
[5]Chemical Science,2021,vol. 12,p. 590 - 598
- 2
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[ 5170-68-3 ]
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[ 19706-16-2 ]
- 3
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[ 19706-16-2 ]
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[ 5170-68-3 ]
- 4
-
[ 5170-68-3 ]
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[ 170961-15-6 ]
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tert-butyl {5-[hydroxy(2,1,3-benzothiazol-4-yl)methyl]thiazol-2-yl}carbamate
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
53% |
|
General procedure: To a stirred solution of 5 (1 equiv.) in THF (~20 mL) was added dropwise a 2.0 M solution of lithium diisopropylamide (LDA) in THF/heptane/ethylbenzene (2.2 equiv.) at -78 C. The reaction mixture was stirred for 30 min at 0 C followed by dropwise addition of aldehyde (1.2equiv.). The solution was stirred for 16 h at room temperature, quenched by a saturated aqueous solution of NH4Cl and extracted with ethyl acetate. The organic phase was dried with MgSO4, evaporated, and the residue was purified by silica gel column chromatography |