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Chemical Structure| 2732-18-5 Chemical Structure| 2732-18-5

Structure of 5,7-Dihydroxycoumarin
CAS No.: 2732-18-5

Chemical Structure| 2732-18-5

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5,7-Dihydroxycoumarin is a coumarin isolated from the inflorescence of Macaranga triloba, showing significant antibacterial activity, making it useful for microbiology and natural product drug development research.

Synonyms: 5,7-dihydroxychromen-2-one

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Product Citations

Product Citations

Uchida, Kai ; Akashi, Tomoyoshi ; Hirai, Masami Yokota ;

Abstract: Xanthones are compounds with a di-Ph ether skeleton mainly found in plants and often glycosylated at carbon atoms. Although many C-glycosyltransferases (CGTs) participating in flavone C-glycosylation have been identified, MiCGT from Mangifera indica, adding sugar to an open-chain benzophenone skeleton, is the only identified xanthone biosynthesis-related CGT. Here, we identified two CGTs from Hypericum perforatum that add sugar to the closed-ring xanthone, but not benzophenone. These CGTs catalyze sugar transfer to the C-4 position of norathyriol (1,3,6,7-tetrahydroxyxanthone) to form isomangiferin (1,3,6,7-tetrahydroxyxanthone 4-C-glucoside), a major xanthone C-glucoside. This is the first study to report CGTs that mediate the direct C-glycosylation of xanthone.

Keywords: Hypericum perforatum ; C-glycosyltransferase ; isomangiferin ; norathyriol

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Product Details of 5,7-Dihydroxycoumarin

CAS No. :2732-18-5
Formula : C9H6O4
M.W : 178.14
SMILES Code : O=C1C=CC2=C(O1)C=C(O)C=C2O
Synonyms :
5,7-dihydroxychromen-2-one
MDL No. :MFCD00488354
InChI Key :KIQQFVJHWNCGAU-UHFFFAOYSA-N
Pubchem ID :5324654

Safety of 5,7-Dihydroxycoumarin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Related Pathways of 5,7-Dihydroxycoumarin

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.61mL

1.12mL

0.56mL

28.07mL

5.61mL

2.81mL

56.14mL

11.23mL

5.61mL

 

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