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Chemical Structure| 477585-40-3 Chemical Structure| 477585-40-3

Structure of 477585-40-3

Chemical Structure| 477585-40-3

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Product Details of [ 477585-40-3 ]

CAS No. :477585-40-3
Formula : C17H13NO2
M.W : 263.29
SMILES Code : O=C(O)C1=CC=C(C2=CC(C)=NC3=CC=CC=C23)C=C1

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Application In Synthesis of [ 477585-40-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 477585-40-3 ]

[ 477585-40-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50488-44-3 ]
  • 1-methylcarboxyphenylboronic acid [ No CAS ]
  • [ 477585-40-3 ]
YieldReaction ConditionsOperation in experiment
With sodium hydrogencarbonate;Pd(PPh3)4; In tetrahydrofuran; aq K2CO3; ethyl acetate; Example 220 4-(2-methyl-4-quinolinyl)benzoic Acid To 1-methylcarboxyphenylboronic acid (1.0 g, 5.6 mmol) and <strong>[50488-44-3]4-bromo-2-methylquinoline</strong> (1.24 g, 5.6 mmol) in THF/aq K2CO3 was added Pd(PPh3)4 and the reaction was heated to 70 C. for 16 hr. Aqueous workup using NaHCO3 and EtOAc, column chromatography and saponification using the same conditions as for Example 214 gave the final productproduct. MS found: (M+H) 264.
 

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