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Chemical Structure| 92-88-6

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Product Details of 4,4'-Dihydroxybiphenyl

CAS No. :92-88-6
Formula : C12H10O2
M.W : 186.21
SMILES Code : C2=C(C1=CC=C(O)C=C1)C=CC(=C2)O
MDL No. :MFCD00002348
InChI Key :VCCBEIPGXKNHFW-UHFFFAOYSA-N
Pubchem ID :7112

Safety of 4,4'-Dihydroxybiphenyl

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H312-H315-H318-H411
Precautionary Statements:P273-P264-P280-P391-P337+P313-P302+P352+P312
Class:9
UN#:3077
Packing Group:

Application In Synthesis of 4,4'-Dihydroxybiphenyl

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 92-88-6 ]
  • Downstream synthetic route of [ 92-88-6 ]

[ 92-88-6 ] Synthesis Path-Upstream   1~3

  • 1
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  • [ 20601-38-1 ]
YieldReaction ConditionsOperation in experiment
96.7 %Chromat. With hydrogen In isopropyl alcohol at 150℃; for 2 h; Autoclave; Industrial scale A 300-mL autoclave equipped with a stirring device was charged with 20 g of 4,4'-biphenol, 1 g of Raney nickel, and 80 g of 2-propanol, and a hydrogenation reaction was carried out for 2 hours at a hydrogen pressure of 6 MPa and a reaction temperature of 150°C. 2-Propanol was added to the obtained reaction solution until the crystals had completely dissolved.
Then, filtration was carried out to obtain a reaction product solution from which the catalyst had been removed.
Then, 21.4 g of crude 4,4'-bicyclohexanol (A) (purity: 96.7percent) was obtained by concentrating and drying this reaction product solution.
References: [1] Chemistry - A European Journal, 2009, vol. 15, # 28, p. 6953 - 6963.
[2] Collection of Czechoslovak Chemical Communications, 1974, vol. 39, p. 249 - 256.
[3] Patent: US4910350, 1990, A, .
[4] Patent: EP2837615, 2015, A1, . Location in patent: Paragraph 0045.
[5] Advanced Synthesis and Catalysis, 2018, vol. 360, # 20, p. 3924 - 3929.
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  • [ 20601-38-1 ]
  • [ 16715-88-1 ]
  • [ 105640-07-1 ]
References: [1] Organic Letters, 2015, vol. 17, # 13, p. 3218 - 3221.
  • 3
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  • [ 20601-38-1 ]
  • [ 16715-88-1 ]
References: [1] Organic Letters, 2015, vol. 17, # 13, p. 3218 - 3221.
 

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