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Chemical Structure| 383142-69-6 Chemical Structure| 383142-69-6

Structure of 383142-69-6

Chemical Structure| 383142-69-6

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Product Details of [ 383142-69-6 ]

CAS No. :383142-69-6
Formula : C10H6FNOS
M.W : 207.22
SMILES Code : O=CC1=NC(C2=CC=C(F)C=C2)=CS1
MDL No. :MFCD02665748

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Application In Synthesis of [ 383142-69-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 383142-69-6 ]

[ 383142-69-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1765-93-1 ]
  • [ 167366-05-4 ]
  • [ 383142-69-6 ]
YieldReaction ConditionsOperation in experiment
32.9% General procedure: Bromoarylaldehyde (1 mmol), aryl or alkenyl-boronicacid (1.2 mmol), and Cs2CO3(2.5 mmol) were dissolved orsuspended in a mixture of 1,4-dioxane (10 mL) and water (5 mL). The resulting mixture was stirred at RT for 5min. Tetrakis (triphenylphosphine) palladium(0) (0.05mmol) was added and the mixture was refluxed for 4-6 h under N2 protection. After cooling to RT, the mixture was dilutedwith CH2Cl2 (10 mL) and the separated aqueous layer wasextracted with CH2Cl2 (3 × 10 mL). The combined organic layers were dried over Na2SO4,filtered, and the solution was concentrated in vacuo to obtain a residue, whichwas purified by silica gel CC using ethyl acetate-petroleum ether gradientelution (1:200-1:4, v/v) to afford the aldehydes.
 

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