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Structure of 351003-10-6

Chemical Structure| 351003-10-6

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Product Details of [ 351003-10-6 ]

CAS No. :351003-10-6
Formula : C8H9NO2
M.W : 151.16
SMILES Code : O=CC1=CC=C(OC)C(N)=C1
MDL No. :MFCD07787578
InChI Key :IXWVKDLWPHIKHS-UHFFFAOYSA-N
Pubchem ID :14984642

Safety of [ 351003-10-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 351003-10-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 351003-10-6 ]

[ 351003-10-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 31680-08-7 ]
  • [ 351003-10-6 ]
YieldReaction ConditionsOperation in experiment
77% With sodium dithionite; potassium carbonate; In dichloromethane; water; 3-Amino-4-methoxybenzaldehyde was obtained by reduction of the corresponding nitro compound according to Tetrahedron Letters, 1993, 34(46), 7445-1446.
With acetic acid;iron; In ethanol; water; at 75℃; for 1h; Reference Production Example 29To a mixture of 1.2 ml of acetic acid, 51 ml of water and 79 ml of ethanol was added 10.04 g of iron powder, and 5.44 g of <strong>[31680-08-7]4-methoxy-3-nitrobenzaldehyde</strong> was added thereto at 75C and stirred for 1 hour. The reaction mixture was filtered and the precipitate was washed with ethyl acetate. A saturated aqueous sodium hydrogencarbonate solution and ethyl acetate were added to the filtrate to effect extraction. The organic layer was dried over anhydrous sodium sulfate and then concentrated under reduced pressure to obtain 4.44 g of 3-amino-4-methoxybenzaldehyde .3-Amino-4-methoxybenzaldehyde:1H-NMR (CDCl3) <5 : 9.80 (IH, s) , 7.27 (IH, dd, J = 8.2, 2.0 Hz), 7.23 (IH, d, J = 2.0 Hz), 6.88 (IH, d, J = 8.2 Hz), 3.97 (2H, br s) , 3.94 (3H, s) .
 

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