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Chemical Structure| 34586-27-1 Chemical Structure| 34586-27-1

Structure of 34586-27-1

Chemical Structure| 34586-27-1

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Product Details of [ 34586-27-1 ]

CAS No. :34586-27-1
Formula : C8H8ClNO2
M.W : 185.61
SMILES Code : O=[N+](C1=CC(C(Cl)C)=CC=C1)[O-]
MDL No. :MFCD07343852

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Application In Synthesis of [ 34586-27-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 34586-27-1 ]

[ 34586-27-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5400-78-2 ]
  • [ 34586-27-1 ]
YieldReaction ConditionsOperation in experiment
With thionyl chloride; In dichloromethane; at 0 - 35℃; Thionyl chloride (162ul, 8.9 mmol) was added dropwise to a solution of l-(3-nitro-phenyl)-ethanol (4.4 mmol) in DCM (50 ml) at 0 0C. The reaction was stirred at room temperature for 2 h. Further thionyl chloride (162 mul, 8.9 mmol) was added and the reaction stirred at 35 0C for 24 h. The mixture was evaporated to give the desired product as a yellow oil. NMR (DMSO) shows 70%, together with 3-nitrostyrene impurity. Used in the next step without further purification.
 

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