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Chemical Structure| 332-29-6 Chemical Structure| 332-29-6

Structure of 332-29-6

Chemical Structure| 332-29-6

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Product Details of [ 332-29-6 ]

CAS No. :332-29-6
Formula : C8H8FNO
M.W : 153.15
SMILES Code : O=C(N)CC1=CC=C(F)C=C1
MDL No. :MFCD03576227

Safety of [ 332-29-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 332-29-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 332-29-6 ]

[ 332-29-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 459-04-1 ]
  • [ 332-29-6 ]
YieldReaction ConditionsOperation in experiment
With ammonium acetate; In acetone; at 20℃; for 17h; The acid chloride was dissolved in acetone (200 ml). Ammonium acetate (112 g) was added to the solution, and the mixture was stirred at room temperature for 17 hr. An aqueous saturated sodium hydrogencarbonate solution (150 ml) was added thereto, and the mixture was stirred at room temperature for one hr. The reaction solution was then extracted with chloroform, and the solvent in the extract was removed by evaporation to give a crude crystal. The resultant crude crystal was washed with a hexane/ethyl acetate (2/1) mixed solution to give 4-fluorophenylacetamide (10.5 g, yield 70%). 1H-NMR (CDCl3, 400 MHz): δ 3.53 (s, 2H), 5.25 - 5.70 (m, 2H), 7.00 - 7.05 (m, 2H), 7. 20 - 7.26 (m, 2H)
 

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