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Chemical Structure| 310459-43-9 Chemical Structure| 310459-43-9

Structure of 310459-43-9

Chemical Structure| 310459-43-9

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Product Details of [ 310459-43-9 ]

CAS No. :310459-43-9
Formula : C11H6ClFO2
M.W : 224.62
SMILES Code : O=CC1=CC=C(C2=CC=C(F)C(Cl)=C2)O1
MDL No. :MFCD00658941

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Application In Synthesis of [ 310459-43-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 310459-43-9 ]

[ 310459-43-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 27329-70-0 ]
  • [ 156150-67-3 ]
  • [ 310459-43-9 ]
YieldReaction ConditionsOperation in experiment
80% With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,2-dimethoxyethane; ethanol; water; at 65℃; for 1h; General procedure: 1.00 mmol arylhalide, 1.30 mmol furfural-boronic acid and 0.05 mmolBis(triphenylphosphine)palladium(II) dichloride were treated with 0.30 mLdimethoxyethane, 0.50 mL ethanol and 0.30 mL aqueous 2M sodium carbonate solution.The reaction was heated to 65C for 1h or until the TLC showed no remaining startingmaterial. The mixture was evaporated and extracted three times with ethyl acetate. Thecombined organic layers were washed with brine, dried over MgSO4, filtered andconcentrated. The crude product was purified by column chromatography usinghexanes/ethyl acetate (9:1).
 

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