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Chemical Structure| 28615-70-5 Chemical Structure| 28615-70-5

Structure of 28615-70-5

Chemical Structure| 28615-70-5

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Product Details of [ 28615-70-5 ]

CAS No. :28615-70-5
Formula : C10H6BrNO
M.W : 236.06
SMILES Code : O=CC1=NC2=CC=CC=C2C(Br)=C1
MDL No. :MFCD08705667

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Application In Synthesis of [ 28615-70-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 28615-70-5 ]

[ 28615-70-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50488-44-3 ]
  • [ 28615-70-5 ]
YieldReaction ConditionsOperation in experiment
78% With selenium(IV) oxide; In 1,4-dioxane; at 80℃; for 2h; <strong>[50488-44-3]4-Bromo-2-methylquinoline</strong> (0.995 g, 4.48 mmol), selenium dioxide (0.99 g, 8.9 mmol) and1,4-dioxane (25 mL) were added to a 100 mL single-neck flask. After the addition, the reaction mixture was stirred at 80 C for 2 h. The reaction mixture was cooled to room temperature andfiltered to remove the insoluble substance, then the filtrate was concentrated in vacuo. The residue was purified by silica-gel column chromatography (ethyl acetate/petroleum ether (v/v) = 1/10) to give the title compound as a pale yellow solid (0.825 g, 78%).MS (ES-API, pos. ion) m/z: 236.9 [M + 2]t
 

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