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Chemical Structure| 276862-76-1 Chemical Structure| 276862-76-1

Structure of 276862-76-1

Chemical Structure| 276862-76-1

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Product Details of [ 276862-76-1 ]

CAS No. :276862-76-1
Formula : C4H10ClNO2
M.W : 139.58
SMILES Code : O[C@H]1CNC[C@@H]1O.[H]Cl
MDL No. :MFCD11054831

Safety of [ 276862-76-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 276862-76-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 276862-76-1 ]

[ 276862-76-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 90365-74-5 ]
  • [ 276862-76-1 ]
YieldReaction ConditionsOperation in experiment
97% The (3S,4S)-l-benzylpyrrolidine-3,4-diol (0.52 g, 2.7 mmol) was dissolved in ethanol (15 ml) and acetic acid (10 ml) and hydrogenated (50 psi H2) over 10percent Pd-C (100 mg) on a Parr apparatus for 6 hours. After filtering through Celite, and washing the filter cake with ethyl acetate, the combined filtrate and washings were concentrated. The residue was diluted with 4N HCl/dioxane (2 ml), methanol (5 ml), then toluene (40 ml) and concentrated. The residue was triturated with ethyl ether to provide the hydrochloride salt of the title compound as a tan solid (0.37 g, 97percent). 1H NMR (D2O, 400MHz) 4.35 (d, J=3.4 Hz, 2H), 3.54 (dd, J = 12.8 Hz, 3.4 Hz, 2H), 3.30 (d, J = 12.8 Hz, 2H).
 

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